N-叔丁氧羰基-3-(4-氰苯基)哑嗪合成路线 （共 28 条）
反应条件
in chloroform-d1 T=19°C; other solvents, temperature; Product distribution;
参考文献
Chemistry - A European Journal, , vol. 3, # 10 p. 1691 - 1709
参考文献
Tetrahedron Letters, , vol. 46, # 13 p. 2207 - 2210
反应条件
lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 1.) 30 min, 2.) 30 min;
参考文献
Vidal, Joelle; Damestoy, Stephanie; Guy, Laure; Hannachi, Jean-Christophe; Aubry, Andre; Collet, Andre
Chemistry - A European Journal, 1997 , vol. 3, # 10 p. 1691 - 1709
反应条件
in tetrahydrofuran T=-78°C; 0.5 h;
参考文献
Vidal, Joelle; Guy, Laure; Sterin, Sebastien; Collet, Andre
Journal of Organic Chemistry, 1993 , vol. 58, # 18 p. 4791 - 4793
反应条件
1: phenyllithium With zinc(II) chloride in diethyl ether; hexane T=0°C; 0.5 h; Inert atmosphere; 2: N-(tert-butoxycarbonyl)-3-(4-cyanophenyl)-oxaziridine in diethyl ether; hexane T=0°C; 2 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 49, # 52 p. 7383 - 7385
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=0°C; 1.41667 h;
参考文献
F. HOFFMANN-LA ROCHE AG; GRETHER, Uwe; HEBEISEN, Paul; MOHR, Peter; RICKLIN, Fabienne; ROEVER, Stephan
Patent: WO2013/37703 A1, 2013 ;
Location in patent: Page/Page column 62 ;
反应条件
in chloroform-d1 T=19°C; other solvents, temperature; Product distribution;
参考文献
Vidal, Joelle; Damestoy, Stephanie; Guy, Laure; Hannachi, Jean-Christophe; Aubry, Andre; Collet, Andre
Chemistry - A European Journal, 1997 , vol. 3, # 10 p. 1691 - 1709
反应条件
1: 4-MeOC6H4Li With zinc(II) chloride in diethyl ether; hexane T=0°C; 0.5 h; Inert atmosphere; 2: N-(tert-butoxycarbonyl)-3-(4-cyanophenyl)-oxaziridine in diethyl ether; hexane T=0°C; 1.5 h; Inert atmosphere;
参考文献
Ghoraf, Mohammed; Vidal, Joelle
Tetrahedron Letters, 2008 , vol. 49, # 52 p. 7383 - 7385
反应条件
1: cyclohexyl-lithium With zinc(II) chloride in diethyl ether; hexane
T=0°C; 0.5 h; Inert atmosphere;
2: N-(tert-butoxycarbonyl)-3-(4-cyanophenyl)-oxaziridine in diethyl ether; hexane
T=0°C; 2 h; Inert atmosphere;
参考文献
Ghoraf, Mohammed; Vidal, Joelle
Tetrahedron Letters, 2008 , vol. 49, # 52 p. 7383 - 7385
反应条件
1: CD2Cl2 / -94 °C
2: toluene / 111 h / Heating
View Scheme
参考文献
Vidal, Joelle; Damestoy, Stephanie; Guy, Laure; Hannachi, Jean-Christophe; Aubry, Andre; Collet, Andre
Chemistry - A European Journal, 1997 , vol. 3, # 10 p. 1691 - 1709
