反应条件
1: 84 percent / t-BuLi / tetrahydrofuran / 1.) -78 deg C, 2.5 h; 2.) RT 2: 1.) Ac2O; 2.) NaBH4 / 1.) THF, RT, 2 h; 2.) MeOH, RT, 4 h 3: 75 percent / aq. HCl, NaBH3CN / ethanol / 4 h / -30 °C 4: 1.) Proton Sponge; 2.) HCl/EtOH / 1.) 1,2-dichloroethane, reflux, 5 h; 2.) EtOH, reflux, 3 h View Scheme
参考文献
Tetrahedron, , vol. 49, # 41 p. 9183 - 9190
