(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
(1S)-(+)-3-exo-(dimethylamino)isoborneol in toluene T=0°C; 70 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organometallic Chemistry, , vol. 382, # 1-2 p. 19 - 37
反应条件
Candida antarctica lipase in diethyl ether T=95°C; 0.0833333 h; Irradiationwithout MW irradiation; other temperature, reaction time; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 61, # 22 p. 7746 - 7749
反应条件
Bacillus subtilis precultivation 1 day, incubation time 30 min;
参考文献
Journal of Organic Chemistry, , vol. 63, # 22 p. 7598 - 7599
反应条件
potassium hydroxide; dimethylmalonyl (1R,2R)-N,N'-bis[2-(aminocyclohexyl)]diamide; tris(triphenylphosphine)ruthenium(II) chloride T=20°C; 24 h; Product distribution; Further Variations:Reagents;
参考文献
Tetrahedron Letters, , vol. 41, # 46 p. 8999 - 9003
反应条件
BES buffer; subtilisin Carlsberg (EC 3.4.21.62) in acetonitrile T=30°C; pH=7.2; 6 h; Product distribution; Further Variations:Reagents;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 10-11 p. 1183 - 1192
反应条件
Candida antarctica lipase B in tetrahydrofuran 16 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Organic Process Research and Development, , vol. 13, # 4 p. 706 - 709
反应条件
1: With Candida antarctica lipase B in tetrahydrofuran 16 h; Enzymatic reaction; 2: With hydrogenchloride; water in methanol optical yield given as percent ee;
参考文献
Organic Process Research and Development, , vol. 13, # 4 p. 706 - 709
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 24 h / 30 °C / pH 6.5 View Scheme
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
反应条件
T=4°C; chloroperoxidase from Caldariomyces fumago in citrate buffer as catalyst; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 57, # 28 p. 7265 - 7270
反应条件
oxonium; methyllithium 1.) ether; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 22, # 44 p. 4417 - 4420
