(R)-(+)-1-苯基乙醇合成路线 (共 353 条)
反应条件
hydroxide; triphenylphosphine; diethylazodicarboxylate 1.) THF, - 30 deg C; ee(S) : 68percent. Var. temp.; Multistep reaction. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 22, # 52 p. 5279 - 5282
反应条件
sodium; aluminum dichloride hydride 1.) ether, 0 deg C, 2 h; 2.) liquid ammonia; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 5 p. 334 - 335
反应条件
Pseudomonas cepacia lipase in diethyl ether T=77°C; 3 h; Irradiationwithout MW irradiation; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 61, # 22 p. 7746 - 7749
反应条件
Candida antarctica lipase in diethyl ether T=90°C; 0.25 h; Irradiationwithout MW irradiation; other temperature, reaction time; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 61, # 22 p. 7746 - 7749
反应条件
Pseudomonas cepacia lipase in diethyl ether T=85°C; 0.25 h; Irradiationwithout MW irradiation; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 61, # 22 p. 7746 - 7749
反应条件
water; acetic acid; sodium nitrite 1.) RT, 18 h, 2.) 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 13 p. 2193 - 2198
反应条件
(-)-2,3-O-isopropylidene-1,1,4,4-tetraphenyl-L-threitol; tantalum pentachloride in dichloromethane 40 h; Ambient temperatureenantioselective acylation of various secondary alcohols with other chiral reagent; kinetic resolution; Product distribution;
参考文献
Tetrahedron Letters, , vol. 39, # 20 p. 3263 - 3266
反应条件
methylmagnesium bromide in dichloromethane T=0°C; Acylation; 6 h; Product distribution; Further Variations:SolventsTemperaturesReagents;
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9365 - 9373
反应条件
cells of Geotrichum candidum in water T=30°C; 24 h; Product distribution;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 22 p. 3147 - 3153
反应条件
water T=30°C; 168 h; asymmetric hydrolysis and resolution by Pseudomonas cepacia; Product distribution;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 58, # 7 p. 1330 - 1331