(R)-(+)-环氧丙烷合成路线 （共 61 条）
反应条件
copper(l) iodide in tetrahydrofuran T=-20°C; 12 h;
参考文献
Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep
Tetrahedron Letters, 2009 , vol. 50, # 51 p. 7188 - 7190
反应条件
copper(l) iodide in tetrahydrofuran T=-40°C; Inert atmosphere;
参考文献
Schmidt, Bernd; Kunz, Oliver
European Journal of Organic Chemistry, 2012 , # 5 p. 1008 - 1018
反应条件
1: trans vinyl bromide With magnesium; ethylene dibromide in tetrahydrofuran 0.5 h; 2: (R)-(+)-propylene oxide in tetrahydrofuran T=-40°C; 4 h;
参考文献
Yadav; Kumar, N. Niranjan; Reddy, M. Sridhar; Prasad
Tetrahedron, 2007 , vol. 63, # 12 p. 2689 - 2694
参考文献
TARGACEPT, INC.
Patent: WO2006/53039 A2, 2006 ;
Location in patent: Page/Page column 42 ;
反应条件
monofluoromethane T=25°C; P=720 Torr; Irradiationalso in the presence of H2O or CH4; Product distributionMechanism;
参考文献
Troiani, Anna; Filippi, Antonello; Speranza, Maurizio
Chemistry - A European Journal, 1997 , vol. 3, # 12 p. 2063 - 2070
反应条件
triethylamine; lithium chloride in ethanol T=70°C; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 6 p. 1976 - 1980
反应条件
in water; acetonitrile T=28°C; 20 - 24 h;
参考文献
US2007/249610 A1, ;
Page/Page column 5; 8-9 ;
反应条件
(i) Mg, THF, (ii) CuI; Multistep reaction;
参考文献
Johnston; Slessor
Canadian Journal of Chemistry, 1979 , vol. 57, # 2 p. 233 - 235
反应条件
N,N'-dimethyl-N,N'-propyleneurea; anhydrous 4,4'-bipyridyl; bis(cyclopentadienyl)titanium dichloride; manganese; NiCl2*0.97C2H6O; triethyl amine hydrochloride T=20°C; 12 h; Inert atmosphereGlovebox;
参考文献
Zhao, Yang; Weix, Daniel J.
Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 48 - 51
反应条件
1: propyl bromide With methylmagnesium bromide; magnesium in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 2: (R)-(+)-propylene oxide With copper dilithium tetrachloride in tetrahydrofuran T=-78 - 20°C; 1.5 h; Inert atmosphere; 3: With water; ammonium chloride in tetrahydrofuran Inert atmosphereCooling with ice;
参考文献
Taguri, Tomonori; Yamakawa, Rei; Fujii, Toru; Muraki, Yuta; Ando, Tetsu
Tetrahedron Asymmetry, 2012 , vol. 23, # 11-12 p. 852 - 858
