4-(3-丁烯-1-基)苯甲腈合成路线 （共 11 条）
反应条件
1: 4-bromo-but-1-ene With iodine; zinc in N,N-dimethyl acetamide T=80°C; 2: para-bromobenzonitrile With tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl acetamide T=20°C; Further stages.;
参考文献
Organic Letters, , vol. 5, # 4 p. 423 - 425
反应条件
1: 4-cyanotoluene With N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide in tetrahydrofuran; hexane T=-78°C; Metallation; 0.25 h; 2: allyl bromide in tetrahydrofuran; hexane T=-78°C; Alkylation; 0.5 h;
参考文献
Bunce, Richard A.; Johnson, Lara B.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 407 - 412
参考文献
Panteleeva, Elena V.; Haufe, Guenter; Shteingarts, Vitalij D.
Synlett, 2007 , # 10 p. 1616 - 1618
反应条件
potassium in ammonia T=-33°C; effect of cyano-group on mechanism of reaction of arene radical anions; Product distributionMechanism;
参考文献
Tetrahedron Letters, , vol. 36, # 46 p. 8465 - 8466
反应条件
1: (i) Mg, (ii) /BRN= 605308/ 2: dimethylformamide / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 33, # 3 p. 972 - 977
反应条件
cadmium 1.) THF, 0 deg C, 5 h, 2.) THF, 4 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 50, # 3 p. 416 - 417
反应条件
in N,N-dimethyl-formamide Heating;
参考文献
Journal of Organic Chemistry, , vol. 33, # 3 p. 972 - 977
反应条件
1.) K 1.) liquid NH3, THF, -80 - -90 deg C, 5 min, 2.) THF, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Russian Journal of Organic Chemistry, , vol. 30, # 6.2 p. 941 - 950
Zhurnal Organicheskoi Khimii, , vol. 30, # 6 p. 882 - 891
反应条件
hydrogen; palladium on activated charcoal; ethylenediamine in tetrahydrofuran T=20°C; 24 h; atmospheric pressure;
参考文献
Maegawa, Tomohiro; Fujita, Yuki; Sakurai, Ai; Akashi, Akira; Sato, Mutsumi; Oono, Keiji; Sajiki, Hironao
Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 5 p. 837 - 839
反应条件
sodium hydroxide in ethanol Heating;
参考文献
Peterson,P.E. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 3 p. 972 - 977
