1-(硫代苯甲酰基)哌啶合成路线 （共 35 条）
反应条件
dithiophosphoric acid O,O-diethyl ester in toluene
6 h; Heating;
参考文献
Borthakur, Naleen
Tetrahedron Letters, 1995 , vol. 36, # 37 p. 6745 - 6746
反应条件
1: 94 percent / 5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphinan / benzene / 2 h / Heating
2: 97.7 percent / Et3N / benzene
View Scheme
参考文献
Doszczak, Leszek; Rachon, Janusz
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 10 p. 1271 - 1279
反应条件
1: 98 percent / pyridine / benzene / 0.25 h
2: 94 percent / 5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane / benzene / 2 h / Heating
3: 98 percent / NEt3 / benzene
View Scheme
参考文献
Doszczak; Rachon
Chemical Communications, 2000 , # 21 p. 2093 - 2094
反应条件
in dichloromethane
1 h; Ambient temperature;
参考文献
Kato, Shinzi; Hattori, Eiji; Sato, Hiroyuki; Mizuta, Masateru; Ishida, Masaru
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1981 , vol. 36, # 7 p. 783 - 790
反应条件
1: 68 percent / Et3N / CH2Cl2 / 2 h / 0 - 25 °C
2: imidazole / CH2Cl2 / 2 h / 25 °C
3: Lawesson's reagent / tetrahydrofuran / 12 h / 25 °C
4: Bu4NF / tetrahydrofuran / 0.5 h / 25 °C
5: 71 percent / Ph3P, DIAD / tetrahydrofuran / 4 h / -60 - 25 °C
View Scheme
参考文献
Wipf, Peter; Hayes, Gregory B.
Tetrahedron, 1998 , vol. 54, # 25 p. 6987 - 6998
反应条件
1: imidazole / CH2Cl2 / 2 h / 25 °C
2: Lawesson's reagent / tetrahydrofuran / 12 h / 25 °C
3: Bu4NF / tetrahydrofuran / 0.5 h / 25 °C
4: 71 percent / Ph3P, DIAD / tetrahydrofuran / 4 h / -60 - 25 °C
View Scheme
参考文献
Wipf, Peter; Hayes, Gregory B.
Tetrahedron, 1998 , vol. 54, # 25 p. 6987 - 6998
反应条件
in methanol
T=20°C; 0.5 h;
参考文献
Kolakowski, Robert V.; Shangguan, Ning; Williams, Lawrence J.
Tetrahedron Letters, 2006 , vol. 47, # 7 p. 1163 - 1166
反应条件
1: CH2Cl2 / 0.25 h / 20 °C
2: 94 percent / 5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphinan / benzene / 2 h / Heating
3: 97.7 percent / Et3N / benzene
View Scheme
参考文献
Doszczak, Leszek; Rachon, Janusz
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 10 p. 1271 - 1279
反应条件
1: CH2Cl2
2: CH2Cl2 / 0.25 h / 20 °C
3: 94 percent / 5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphinan / benzene / 2 h / Heating
4: 97.7 percent / Et3N / benzene
View Scheme
参考文献
Doszczak, Leszek; Rachon, Janusz
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 10 p. 1271 - 1279
反应条件
triethylamine in chloroform
0.5 h;
参考文献
Corsaro, Antonino; Compagnini, Anna; Perrini, Giancarlo; Purrello, Giovanni
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 5 p. 897 - 900
