3-碘-氮杂丁烷-1-羧酸叔丁酯合成路线 （共 6 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 4 h;
参考文献
Kiesewetter, Dale O.; Eckelman, William C.
Journal of Labelled Compounds and Radiopharmaceuticals, 2004 , vol. 47, # 13 p. 953 - 969
反应条件
1: With di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=20°C; Mitsunobu reaction;
2: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C;
参考文献
Yoakim, Christiane; Guse; O'Meara; Thavonekham
Synlett, 2003 , # 4 p. 473 - 476
反应条件
triphenylphosphine in tetrahydrofuran
参考文献
Pfizer Inc
Patent: US5936089 A1, 1999 ;
参考文献
Shima, Ichiro; Ohkawa, Takehiko; Sato, Kentaro; Ishibashi, Naoki; Imamura, Kenichiro
Patent: US2004/97425 A1, 2004 ;
反应条件
1: NaOH / tetrahydrofuran; H2O
2: 1.37 g / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Kiesewetter, Dale O.; Eckelman, William C.
Journal of Labelled Compounds and Radiopharmaceuticals, 2004 , vol. 47, # 13 p. 953 - 969
反应条件
1: NaOH / tetrahydrofuran; H2O
2: 1.37 g / triphenylphosphine; diisopropyl azodicarboxylate / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Kiesewetter, Dale O.; Eckelman, William C.
Journal of Labelled Compounds and Radiopharmaceuticals, 2004 , vol. 47, # 13 p. 953 - 969
