4-氯-3-硝基苯甲酸叔丁酯合成路线 （共 7 条）
反应条件
thionyl chloride in tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide
参考文献
Cancer Research Campaign Technology Limited
Patent: US5985909 A1, 1999 ;
反应条件
thionyl chloride in tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide
参考文献
Auckland Uniservices Limited
Patent: US6071908 A1, 2000 ;
反应条件
in DMF (N,N-dimethyl-formamide) T=20°C; 1 h;
参考文献
BAYER HEALTHCARE AG
Patent: WO2005/28451 A1, 2005 ;
Location in patent: Page/Page column 36 ;
反应条件
n-butyllithium in tert-butyl alcohol
参考文献
G. D. Searle and Co.
Patent: US5304644 A1, 1994 ;
US 5304644 A
反应条件
sulfuric acid in dichloromethane T=20°C; 480 h;
参考文献
Van Der Aar, Ellen M.; De Groot, Marcel J.; Bouwman, Tialda; Bijloo, Greetje J.; Commandeur, Jan N. M.; Vermeulen, Nico P. E.
Chemical Research in Toxicology, 1997 , vol. 10, # 4 p. 439 - 449
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=0 - 20°C; 17 h; Inert atmosphere;
参考文献
Skouta, Rachid; Dixon, Scott J.; Wang, Jianlin; Dunn, Denise E.; Orman, Marina; Shimada, Kenichi; Rosenberg, Paul A.; Lo, Donald C.; Weinberg, Joel M.; Linkermann, Andreas; Stockwell, Brent R.
Journal of the American Chemical Society, 2014 , vol. 136, # 12 p. 4551 - 4556
参考文献
Kim, Mi Kyoung; Yoon, Hyunjun; Barnard, Dale Lynn; Chong, Youhoon
Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 4 p. 486 - 488
