2-甲基-9H-噻吨-9-酮合成路线 （共 15 条）
反应条件
trifluorormethanesulfonic acid; ytterbium(III) triflate Friedel Crafts reaction; 0.0666667 h; Neat (no solvent)Microwave irradiation;
参考文献
Li, Jie; Jin, Can; Su, Weike
Heterocycles, 2011 , vol. 83, # 4 p. 855 - 866
反应条件
1: bis (2-carboxyphenyl)-disulfide With sulfuric acid T=25°C; 1 h; 2: toluene T=20 - 25°C; 2 h;
参考文献
San-Apro Limited
Patent: US8329771 B2, 2012 ;
Location in patent: Page/Page column 23 ;
反应条件
cesium fluoride in tetrahydrofuran T=90°C; 24 h; Title compound not separated from byproducts;
参考文献
Zhao, Jian; Larock, Richard C.
Journal of Organic Chemistry, 2007 , vol. 72, # 2 p. 583 - 588
反应条件
1: 87 percent / K2CO3, KI, copper bronze / dimethylformamide / 18 h / Heating 2: 69 percent / conc. H2SO4 / 1 h / 100 °C View Scheme
参考文献
Filippatos; Papadaki-Valiraki; Roussakis; Verbist
Archiv der Pharmazie, 1993 , vol. 326, # 8 p. 451 - 456
反应条件
1: 87 percent / K2CO3, KI, copper bronze / dimethylformamide / 18 h / Heating 2: 69 percent / conc. H2SO4 / 1 h / 100 °C View Scheme
参考文献
Filippatos; Papadaki-Valiraki; Roussakis; Verbist
Archiv der Pharmazie, 1993 , vol. 326, # 8 p. 451 - 456
反应条件
1: 85 percent / potassium carbonate, copper I iodide, copper bronz / nitrobenzene 2: 60 percent / sulfuric acid View Scheme
参考文献
Mayer
Chemische Berichte, 1910 , vol. 43, p. 590
反应条件
1: 85 percent / potassium carbonate, copper I iodide, copper bronz / nitrobenzene 2: 60 percent / sulfuric acid View Scheme
参考文献
Brindle, Ian D.; Doyle, Paul P.
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1869 - 1871
反应条件
1: pyridine / 0.5 h / Heating 2: P2O5, H3PO4 / 2 h / 120 - 125 °C View Scheme
参考文献
Chhaya, P. N.; Nimbalkar, M. M.; Hosangadi, B. D.
Journal of Organic Chemistry, 1986 , vol. 51, # 23 p. 4458 - 4460
反应条件
1: potassium carbonate / N,N-dimethyl acetamide / 6 h / 170 °C / |Inert atmosphere 2: tetrabutylammomium bromide; tert.-butylhydroperoxide / water / 24 h / 120 °C / |Schlenk technique; |Sealed tube; |Inert atmosphere View Scheme
参考文献
Rao, Honghua; Ma, Xinyi; Liu, Qianzi; Li, Zhongfeng; Cao, Shengli; Li, Chao-Jun
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2191 - 2196
反应条件
2: concentrated sulfuric acid / 100 °C View Scheme
参考文献
Mayer
Chemische Berichte, 1910 , vol. 43, p. 590
