2-氨基-5-甲基吡啶合成路线 （共 125 条）
反应条件
[Cu2(bpnp)(OH)(CF3COO)3]; tetrabutylammomium bromide; ammonia; caesium carbonate in water T=110 - 120°C; 16 h; Sealed tube;
参考文献
Liao, Bei-Sih; Liu, Shiuh-Tzung
Catalysis Communications, 2013 , vol. 32, p. 28 - 31
反应条件
hydrogenchloride; 4-chloro-2-methyl-1,3-benzoxazin-2-yl polystyrene 1.) ethylene chloride, reflux, 24 h, 2.) reflux, 20 h; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 26, # 8 p. 2065 - 2068
反应条件
dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate in 1,4-dioxane T=50°C; 24 h; Inert atmosphere; Reagent/catalyst;
参考文献
Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L.
Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737
反应条件
pyridine; sodium hydroxide in dichloromethane; water
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 20°C; 48 h;
参考文献
Adam, Mohamed Shaker S.; Jones, Peter G.; Heinicke, Joachim W.
European Journal of Inorganic Chemistry, 2010 , # 21 p. 3307 - 3316
反应条件
sodium hydroxide; hydrogen bromide; trimethylamine in ethyl acetate
反应条件
hydrogenchloride 8 h; Heating;
参考文献
Wachi, Kazuyuki; Terada, Atsusuke
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 2 p. 465 - 472
反应条件
1: With p-methylbenzenesulfonyl (tosylate); tert-butylamine in various solvent(s) 0.25 h; 2: With trifluoroacetic acid in various solvent(s) T=70°C; Further stages. Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 72, # 12 p. 4554 - 4557
参考文献
Pharmaceutical Chemistry Journal, , vol. 19, # 7 p. 479 - 481
Khimiko-Farmatsevticheskii Zhurnal, , vol. 19, # 7 p. 829 - 832
反应条件
sodium hydroxide; palladium diacetate; triphenylphosphine in ethanol 48 h; RefluxInert atmosphere;
参考文献
Bessmertnykh, Alla; Douaihy, Christiane Morkos; Muniappan, Sankar; Guilard, Roger
Synthesis, 2008 , # 10 art. no. P00808SS, p. 1575 - 1579
