2-氨基-5-甲基吡啶合成路线 （共 125 条）
反应条件
1: water / 0.33 h / 140 °C / |Microwave irradiation; |Inert atmosphere; |Sealed tube 2: ammonium acetate View Scheme
参考文献
Heterocyclic Communications, , vol. 20, # 1 p. 21 - 23
反应条件
sodium amide; xylene
反应条件
1: ethanol / 5 h / 20 °C 2: NaBH4 / tetrahydrofuran / 8 h / Heating 3: 64 percent / conc. H2SO4, fuming HNO3 / 1 h / 20 °C View Scheme
参考文献
Heterocycles, , vol. 38, # 3 p. 529 - 540
反应条件
1: bromine; aqueous sodium nitrite solution; aqueous hydrobromic acid 2: aqueous KMnO4 3: aqueous HCl View Scheme
参考文献
Bradlow; Vanderwerf
Journal of Organic Chemistry, 1949 , vol. 14, p. 509,513
反应条件
1: acetic acid 2: aqueous KMnO4 3: aqueous NaOH View Scheme
参考文献
Ferrari
Bollettino Chimico Farmaceutico, 1957 , vol. 96, p. 542,543
反应条件
hydrogen bromide; bromine; sodium nitrite 1.) -20 deg C, 90 min; 2.) 15 deg C, 1 h 45 min;
参考文献
Windscheif; Vogtle
Synthesis, 1994 , # 1 p. 87 - 92
反应条件
sodium hydroxide; bromine; sodium nitrite in water; hydrogen bromide
参考文献
Merck Sharpe and Dohme Ltd.
Patent: US5432177 A1, 1995 ;
反应条件
sodium hydroxide; bromine; sodium hydrogensulfite; sodium nitrite in hexane; water
参考文献
Merck and Co., Inc.
Patent: US4574125 A1, 1986 ;
反应条件
1: acetic acid 2: aqueous KMnO4 3: methanol; HCl View Scheme
参考文献
Ferrari
Bollettino Chimico Farmaceutico, 1957 , vol. 96, p. 542,543
反应条件
1: acetic acid 2: aqueous KMnO4 3: methanol; HCl 4: acetic acid 5: concentrated aqueous NH3 6: concentrated aqueous NH3 / 130 °C View Scheme
参考文献
Ferrari
Bollettino Chimico Farmaceutico, 1957 , vol. 96, p. 542,543
