1-苯基-2-环己基乙烷合成路线 （共 30 条）
反应条件
sodium tetrahydroborate in dichloromethane T=20°C; Rate constant;
参考文献
Giese, Bernd; Kretzschmar, Gerhard
Chemische Berichte, 1983 , vol. 116, # 9 p. 3267 - 3270
反应条件
tetrabutylammomium bromide; tetra-(n-butyl)ammonium iodide; aluminium in N,N-dimethyl-formamide Ambient temperatureelectrolysis;
参考文献
Leonel, Eric; Paugam, Jean Paul; Nedelec, Jean-Yves; Perichon, Jacques
Journal of Chemical Research, Synopses, 1995 , # 7 p. 278 - 279
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere 1.2: 0 - 20 °C 2.1: hydrogen / palladium 10 on activated carbon / ethyl acetate / 8 h / 20 °C View Scheme
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; GRAHAM, Keith; BERNDT, Mathias; CHI, Dae, Yoon; LEE, Byoung, Se; SHINDE, Sandip, S.; KIL, Hee, Seup; LEE, Sang, Ju; RYU, Jin-Sook; OH, Seung, Jun
Patent: WO2011/6610 A1, 2011 ;
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere 1.2: 0 - 20 °C 2.1: hydrogen / palladium 10 on activated carbon / ethyl acetate / 8 h / 20 °C View Scheme
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; GRAHAM, Keith; BERNDT, Mathias; CHI, Dae, Yoon; LEE, Byoung, Se; SHINDE, Sandip, S.; KIL, Hee, Seup; LEE, Sang, Ju; RYU, Jin-Sook; OH, Seung, Jun
Patent: WO2011/6610 A1, 2011 ;
反应条件
aluminium trichloride
参考文献
Schmerling et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 2636,2640
反应条件
Raney Ni-Al alloy; water; potassium hydroxide T=90°C; 7 h;
参考文献
Liu, Guo-Bin; Zhao, Hong-Yun; Dai, Lu; Thiemann, Thies; Tashiro, Hideki; Tashiro, Masashi
Journal of Chemical Research, 2009 , # 9 p. 579 - 581
反应条件
1-phenyl-1-propyne; Cu in tetrahydrofuran T=25°C; 3 h; Schlenk techniqueGlovebox; Reagent/catalyst;
参考文献
Kim, Ju Hyun; Chung, Young Keun
Chemical Communications, 2013 , vol. 49, # 94 p. 11101 - 11103
反应条件
iron(II) flouride; tri-cyclo-hexyl-phosphine in o-xylene T=120°C; 24 h; Inert atmosphereSchlenk techniqueSealed tube; regioselective reaction;
参考文献
Luo, Shuang; Yu, Da-Gang; Zhu, Ru-Yi; Wang, Xin; Wang, Lei; Shi, Zhang-Jie
Chemical Communications, 2013 , vol. 49, # 71 p. 7794 - 7796
反应条件
sodium tetrahydroborate in ethanol
参考文献
Giese,B.; Meister,J.
Chemische Berichte, 1977 , vol. 110, p. 2588 - 2600
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / |Inert atmosphere 1.2: 2 h / 0 °C / |Inert atmosphere; |Schlenk technique 2.1: sodium hydride / tetrahydrofuran / 2 h / |Inert atmosphere; |Schlenk technique 3.1: iron(II) flouride; tri-cyclo-hexyl-phosphine / o-xylene / 24 h / 120 °C / |Inert atmosphere; |Schlenk technique; |Sealed tube View Scheme
参考文献
Luo, Shuang; Yu, Da-Gang; Zhu, Ru-Yi; Wang, Xin; Wang, Lei; Shi, Zhang-Jie
Chemical Communications, 2013 , vol. 49, # 71 p. 7794 - 7796
