1-甲基-2-甲基磺酰基-5-硝基咪唑合成路线 （共 7 条）
反应条件
dihydrogen peroxide; trifluoroacetic acid T=40°C; 1 h;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
1: 45 percent / aq. HNO3 / 1 h 2: 90 percent / TFA; H2O2 / 1 h / 40 °C View Scheme
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
in dimethyl sulfoxide T=80°C; 0.5 h;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
in 1,4-dioxane T=90°C; 2 h;
参考文献
Nagarajan, K.; Arya, V. P.; George, T.; Bhat, G.A.; Kulkarni, Y. S.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 949 - 952
反应条件
sodium hydride
1) 30-40 deg C, 1h, 2) 90 deg C, 1h; Yield given. Multistep reaction;
参考文献
Iivespaeae, Atso O.; Jarumilinta, Rawewan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 923 - 927
反应条件
sodium hydride
Yield given. Multistep reaction;
参考文献
Iivespaeae, Atso O.; Jarumilinta, Rawewan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 923 - 927
反应条件
sodium hydride in N,N-dimethyl-formamide
T=25°C; 5 h;
参考文献
Nagarajan, K.; Arya, V. P.; George, T.; Sudarsanam, V.; Shah, R. K.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 928 - 940
