3,5-二叔丁基-4-羟基苯甲醛合成路线 （共 132 条）
反应条件
in propionic acid
3 h; Heating;
参考文献
Milgrom; Hill; Dempsey
Tetrahedron, 1994 , vol. 50, # 47 p. 13477 - 13484
反应条件
in propionic acid
3 h; Heating; Further byproducts given;
参考文献
Milgrom, Lionel R.; Mofidi, Nasrin; Harriman, Anthony
Tetrahedron, 1989 , vol. 45, # 23 p. 7341 - 7352
反应条件
boron tribromide; propionic acid
1.) reflux, 1.5 h, 2.) dichloromethane, -80 deg C; Multistep reaction;
参考文献
Milgrom, Lionel R.; Mofidi, Nasrin; Jones, Christopher C.; Harriman, Anthony
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 301 - 310
反应条件
boron tribromide; propionic acid; 3-methoxy-benzaldehyde
1.) reflux, 1.5 h, 2.) dichloromethane, -80 deg C; Multistep reaction;
参考文献
Milgrom, Lionel R.; Mofidi, Nasrin; Jones, Christopher C.; Harriman, Anthony
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 301 - 310
反应条件
boron tribromide; 4-methoxy-benzaldehyde; propionic acid
1.) reflux, 1.5 h, 2.) dichloromethane, -80 deg C; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Milgrom, Lionel R.; Mofidi, Nasrin; Jones, Christopher C.; Harriman, Anthony
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 301 - 310
反应条件
1: p-toluenesulfonic acid / benzene / 48 h / Heating
2: K2CO3 / 18-crown-6 / acetone; dimethylformamide / 48 h / Heating
3: HCl / acetone / 40 °C
View Scheme
参考文献
Oda, Katsuo; Hida, Takemasa; Sakata, Terao; Nagai, Masahiko; Sugata, Yoshihide; Masui, Toshiaki; Nogusa, Hideo
Organic Process Research and Development, 2008 , vol. 12, # 3 p. 442 - 446
反应条件
potassium carbonate in acetone
15 h; Heating;
参考文献
Hori, Hitoshi; Nagasawa, Hideko; Ishibashi, Masaki; Uto, Yoshihiro; Hirata, Akihiko; Saijo, Kouichi; Ohkura, Kazuto; Kirk, Kenneth L; Uehara, Yoshimasa
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 10 p. 3257 - 3265
反应条件
sodium acetate in acetic acid
1.5 h; Heating;
参考文献
Teubner,H.-J. et al.
Justus Liebigs Annalen der Chemie, 1978 , p. 757 - 770
反应条件
in para-xylene
6 h; Heating;
参考文献
Ismagilov; Moskva; Mosunova; Romakhin
Russian Journal of General Chemistry, 2001 , vol. 71, # 10 p. 1547 - 1549
反应条件
1: 77.4 percent / dimethylsulfoxide / 40 h / 80 °C
2: 62.9 percent / 1 N aq. NaOH / 2 h / 90 - 100 °C
View Scheme
参考文献
Katsumi; Kondo; Fuse; Yamashita; Hidaka; Hosoe; Takeo; Watanabe
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1619 - 1627
