1: bromoacetic acid methyl ester With zinc in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere; 2: methyl 2-methoxy-2-(piperidin-1-yl)acetate With chloro-trimethyl-silane in tetrahydrofuran T=20°C; 1 h; Inert atmosphere;

1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; aza-Michael addition; 14 h;

3-phenylmethoxypropionaldehyde; potassium carbonate in acetonitrile T=20°C; Michael addition; 72 h;

triethylamine; acetyl chloride 1.) C6H6, 100 deg C, 2 h, 2.) C6H6, 1 h; Yield given. Multistep reaction. Yields of byproduct given;

triethylamine 1.) C6H6, 100 deg C, 2 h, 2.) C6H6, 1h; Yield given. Multistep reaction. Yields of byproduct given;