[(环己基氧基)甲基]苯合成路线 （共 80 条）
反应条件
1: PhBF3(-)K(+) With boron trifluoride diethyl etherate in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
2: ((2-methoxyethoxy)methoxy)cyclohexane in dichloromethane
T=23°C; Inert atmosphere; regioselective reaction;
参考文献
Vo, Cam-Van T.; Mitchell, T. Andrew; Bode, Jeffrey W.
Journal of the American Chemical Society, 2011 , vol. 133, # 35 p. 14082 - 14089
反应条件
1: PhBF3(-)K(+) With boron trifluoride diethyl etherate in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
2: 1-(cyclohexyloxymethoxy)benzene in dichloromethane
T=23°C; Inert atmosphere; regioselective reaction;
参考文献
Vo, Cam-Van T.; Mitchell, T. Andrew; Bode, Jeffrey W.
Journal of the American Chemical Society, 2011 , vol. 133, # 35 p. 14082 - 14089
反应条件
1: PhBF3(-)K(+) With boron trifluoride diethyl etherate in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
2: O-(methoxymethyl)cyclohexanol in dichloromethane
T=23°C; Inert atmosphere; regioselective reaction;
参考文献
Vo, Cam-Van T.; Mitchell, T. Andrew; Bode, Jeffrey W.
Journal of the American Chemical Society, 2011 , vol. 133, # 35 p. 14082 - 14089
反应条件
copper acetylacetonate
3 h; Heating;
参考文献
Sirkecioglu, Okan; Karliga, Bekir; Talinli, Naciye
Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8483 - 8485
反应条件
phenyl trimethylsilyl telluride; zinc(II) iodide in benzene
3 h; Ambient temperature;
参考文献
Nagakawa, Keiichi; Osuka, Masahiro; Sasaki, Kazuaki; Aso, Yoshio; Otsubo, Tetsuo; Ogura, Fumio
Chemistry Letters, 1987 , p. 1331 - 1334
反应条件
PPh3 gold(I) chloro complex; silver trifluoromethanesulfonate in chlorobenzene
T=20°C; 3 h;
参考文献
Asao, Naoki; Aikawa, Haruo; Tago, Sakie; Umetsu, Kazuteru
Organic Letters, 2007 , vol. 9, # 21 p. 4299 - 4302
反应条件
1: 80 percent / trimethylsilyl bromide / IBr / 0.5 h / Ambient temperature
2: 78 percent / sodium alkoxide / diethyl ether
View Scheme
参考文献
Friedrich, Edwin C.; DeLucca, George
Journal of Organic Chemistry, 1983 , vol. 48, # 10 p. 1678 - 1682
反应条件
1: 77 percent / trimethylsilyl bromide / iodine monochloride (ICl) / 1 h / Ambient temperature
2: 78 percent / sodium alkoxide / diethyl ether
View Scheme
参考文献
Friedrich, Edwin C.; DeLucca, George
Journal of Organic Chemistry, 1983 , vol. 48, # 10 p. 1678 - 1682
反应条件
1: trimethylsilyl bromide / IBr / 0.17 h / 80 - 90 °C / 9 Torr
2: 78 percent / sodium alkoxide / diethyl ether
View Scheme
参考文献
Friedrich, Edwin C.; DeLucca, George
Journal of Organic Chemistry, 1983 , vol. 48, # 10 p. 1678 - 1682
反应条件
1: 74 percent / pyridine
2: 80 percent / trimethylsilyl bromide / IBr / 0.5 h / Ambient temperature
3: 78 percent / sodium alkoxide / diethyl ether
View Scheme
参考文献
Friedrich, Edwin C.; DeLucca, George
Journal of Organic Chemistry, 1983 , vol. 48, # 10 p. 1678 - 1682
