3-溴-N,N-二甲基苯胺合成路线 （共 26 条）
反应条件
potassium hydroxide in water 2.33333 h;
参考文献
Nair, Haridasan K.; Lee, Keun; Quinn, Daniel M.
Journal of the American Chemical Society, 1993 , vol. 115, # 22 p. 9939 - 9941
反应条件
dimethyl sulfate in water
反应条件
1: formaldehyd With sulfuric acid in tetrahydrofuran; water T=0°C; 0.166667 h; 2: 3-bromo-aniline in tetrahydrofuran; water 0.333333 h; 3: With sodium tetrahydroborate in tetrahydrofuran; water T=0 - 20°C; 1.5 h;
参考文献
Pastierik, Tomas; Sebej, Peter; Medalova, Jirina; Stacko, Peter; Klan, Petr
Journal of Organic Chemistry, 2014 , vol. 79, # 8 p. 3374 - 3382
反应条件
sodium cyanoborohydride in water; acetonitrile T=20 - 40°C; 3 h;
参考文献
Targacept, Inc.
Patent: US6337351 B1, 2002 ;
Location in patent: Example 13 ;
反应条件
phosphorus pentoxide T=150°C;
参考文献
Journal of the American Chemical Society, , vol. 107, # 23 p. 6452 - 6458
参考文献
Chemische Berichte, , vol. 54, p. 1417
反应条件
potassium fluoride; C94H134O4P2Pd2; silver fluoride in cyclohexane T=130°C; 14 h; Sealed tube; Reagent/catalyst;
参考文献
Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2014 , vol. 136, # 10 p. 3792 - 3795
反应条件
diethyl ether anschliessendes Behandeln mit Kohlendioxid;
参考文献
Gilman; Banner
Journal of the American Chemical Society, 1940 , vol. 62, p. 344
反应条件
tetrakis(triphenylphosphine) palladium(0); cesium fluoride in 1,2-dichloro-ethane T=75°C; 6 h; Inert atmosphereSealed tube;
参考文献
Ramgren, Stephen D.; Garg, Neil K.
Organic Letters, 2014 , vol. 16, # 3 p. 824 - 827
反应条件
1: 3 -bromo -N,N-dimethylaniline With n-butyllithium in diethyl ether; hexane T=0°C; 0.5 h; 2: N,N-dimethyl-formamide in diethyl ether; hexane T=0°C; 0.0833333 h; Further stages.;
参考文献
Austin, Mark; Egan, Oliver J.; Tully, Raymond; Pratt, Albert C.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 23 p. 3778 - 3786
