N-[(苯基甲氧基)羰基]-L-酪氨酸乙酯合成路线 （共 26 条）
反应条件
sodium hydroxide
Ambient temperature;
参考文献
Pearson, Anthony J.; Lee, Kieseung
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2304 - 2313
反应条件
sodium tetrahydroborate; ethanol; lithium iodide
1) THF, reflx, 1 h, 2) THF, reflux, 7 h; Yield given. Multistep reaction;
参考文献
Sudharshan, Manjula; Hultin, Philip G.
Synlett, 1997 , vol. 1997, # 2 p. 171 - 172
反应条件
ethanol; hydrazine hydrate
参考文献
Bergmann; Fruton
Journal of Biological Chemistry, 1937 , vol. 118, p. 405,414
Full Text Show Details
Harington; Pitt Rivers
Biochemical Journal, 1944 , vol. 38, p. 417,419
反应条件
sulfuric acid in dichloromethane
参考文献
Lovett; Portoghese
Journal of Medicinal Chemistry, 1987 , vol. 30, # 7 p. 1144 - 1149
反应条件
1: K2CO3 / dimethylsulfoxide / 16 h / Ambient temperature
2: 86 percent / NaBH4 / ethanol / 7 h / Ambient temperature
3: 341 g / aq. NaOH, n-Bu4NHSO4 / benzene; H2O / 0.5 h / 15 - 20 °C
4: 61 percent / NaI / tetrahydrofuran; H2O / 2.5 h / Heating
5: 21 percent / Zn / 1,2-dimethoxy-ethane / 5.5 h / Heating
6: 86 percent / H2, aq. HCl / Pd-C / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Kohno, Harumichi; Iwakuma, Takeo; Yamada, Koichiro
Synthetic Communications, 1998 , vol. 28, # 11 p. 1935 - 1945
反应条件
1: conc. H2SO4 / CH2Cl2
2: 89.7 percent / 0.25 N NaOH / tetrahydrofuran / 25 °C
View Scheme
参考文献
Wuensch,E.; Jentsch,J.
Chemische Berichte, 1964 , vol. 97, p. 2490 - 2496
