(S)-2-(叠氮甲基)-1-叔丁氧羰基-吡咯烷合成路线 （共 11 条）
反应条件
sodium azide in N,N-dimethyl-formamide T=70°C; 6 h;
参考文献
Saha, Satyajit; Seth, Saona; Moorthy, Jarugu Narasimha
Tetrahedron Letters, 2010 , vol. 51, # 40 p. 5281 - 5286
反应条件
hydrogen azide; di-isopropyl azodicarboxylate; triphenylphosphine in benzene T=0 - 20°C; Mitsunobu Displacement; 0.833333 h;
参考文献
Vega-Penaloza, Alberto; Sanchez-Antonio, Omar; Escudero-Casao, Margarita; Tasnadi, Gabor; Fueloep, Ferenc; Juaristi, Eusebio
Synthesis (Germany), 2013 , vol. 45, # 17 art. no. SS-2013-M0321-OP, p. 2458 - 2468
反应条件
sodium azide in N,N-dimethyl-formamide T=80°C;
参考文献
Huang, Xiaoguang; Chen, Dongliang; Wu, Ning; Zhang, Aiqin; Jia, Zhenhua; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4130 - 4133
反应条件
1: 39.1 g / tetrahydrofuran / 20 °C 2: 66 percent / pyridine / 6 h / 0 °C 3: sodium azide / dimethylsulfoxide / 19 h / 65 °C View Scheme
参考文献
Cambeiro, Xacobe C.; Pericas, Miquel A.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 113 - 124
反应条件
1: 39.1 g / tetrahydrofuran / 20 °C 2: 66 percent / pyridine / 6 h / 0 °C 3: sodium azide / dimethylsulfoxide / 19 h / 65 °C View Scheme
参考文献
Cambeiro, Xacobe C.; Pericas, Miquel A.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 113 - 124
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran
参考文献
Patel, Dinesh; Jacobs, Jeffrey W.; Jain, Rakesh; Ni, Zhi-Jie; Yuan, Zhengyu
Patent: US2002/115863 A1, 2002 ;
反应条件
sodium azide; 15-crown-5 in N,N-dimethyl-formamide T=80°C; 2 h;
参考文献
Tiecco, Marcello; Testaferri, Lorenzo; Bagnoli, Luana; Scarponi, Catalina; Temperini, Andrea; Marini, Francesca; Santi, Claudio
Tetrahedron Asymmetry, 2007 , vol. 18, # 23 p. 2758 - 2767
反应条件
1: lithium aluminium hydride / tetrahydrofuran / 0 - 25 °C 2: 39.1 g / tetrahydrofuran / 20 °C 3: 66 percent / pyridine / 6 h / 0 °C 4: sodium azide / dimethylsulfoxide / 19 h / 65 °C View Scheme
参考文献
Wroblewska, Aneta; Mloston, Grzegorz
Phosphorus, Sulfur and Silicon and the Related Elements, 2013 , vol. 188, # 4 p. 509 - 511
反应条件
1.1: chloroformic acid ethyl ester; triethylamine / -15 °C 1.2: 0 °C 2.1: triethylamine / tetrahydrofuran / 20 °C 3.1: sodium azide / N,N-dimethyl-formamide / 80 °C View Scheme
参考文献
Dahlin, Nils; Bogevig, Anders; Adolfsson, Hans
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 9-10 p. 1101 - 1105
反应条件
1: sodium tetrahydroborate; sodium hydroxide / tetrahydrofuran; water / 20 °C / Inert atmosphere 2: dichloromethane / 2 h / 0 °C / Inert atmosphere 3: sodium azide / N,N-dimethyl-formamide / 24 h / 60 °C View Scheme
参考文献
Fremaux, Juliette; Fischer, Lucile; Arbogast, Thomas; Kauffmann, Brice; Guichard, Gilles
Angewandte Chemie - International Edition, 2011 , vol. 50, # 48 p. 11382 - 11385
