2-氨基-3-羟基吡啶合成路线 （共 143 条）
参考文献
SIRTRIS PHARMACEUTICALS, INC.
Patent: WO2006/94236 A1, 2006 ;
Location in patent: Page/Page column 28 ;
WO 2006/094236 A1
反应条件
1: polyphosphoric acid / Heating
2: 1-methyl-pyrrolidin-2-one
View Scheme
参考文献
Clark,R.L. et al.
Journal of Medicinal Chemistry, 1978 , vol. 21, p. 1158 - 1162
反应条件
ammonium hydroxide; PPA in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; Petroleum ether; benzene
参考文献
Merck and Co., Inc.
Patent: US4038396 A1, 1977 ;
