2,1,3-苯并噻二唑-4,5-二胺合成路线 （共 11 条）
参考文献
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 6 p. 529 - 532
反应条件
sodium dithionite in water
Heating;
参考文献
da Silva Miranda, Fabio; Signori, Aline Maria; Vicente, Juliano; de Souza, Bernardo; Priebe, Jacks Patrick; Szpoganicz, Bruno; Goncalves, Norberto Sanches; Neves, Ademir
Tetrahedron, 2008 , vol. 64, # 22 p. 5410 - 5415
反应条件
sodium dithionite in water
0.166667 h; Heating;
参考文献
Bock, Hans; Haenel, Peter; Neidlein, Richard
Phosphorus and Sulfur and the Related Elements, 1988 , vol. 39, p. 235 - 252
反应条件
(i) NH2OH*HCl, KOH, EtOH, (ii) aq. Na2S2O4; Multistep reaction;
参考文献
Pesin,V.G. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 186 - 188
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, # 2 p. 249 - 253
反应条件
potassium hydroxide; sodium dithionite in ethanol
T=100°C;
参考文献
Uno; Takagi; Tomoeda
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 12 p. 3896 - 3901
反应条件
1: NaN3 / acetone; methanol; H2O
2: P(OEt)3 / ethanol / 130 - 140 °C
3: H2, Et3N / Pd-C / ethanol; acetone / Ambient temperature
4: Na2S2O4, aq. KOH / ethanol / 100 °C
View Scheme
参考文献
Uno; Takagi; Tomoeda
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 12 p. 3896 - 3901
反应条件
1: H2, Et3N / Pd-C / ethanol; acetone / Ambient temperature
2: Na2S2O4, aq. KOH / ethanol / 100 °C
View Scheme
参考文献
Uno; Takagi; Tomoeda
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 12 p. 3896 - 3901
反应条件
potassium hydroxide; sodium disulfite; hydroxylamine hydrochloride
1.) CH3OH; Multistep reaction;
参考文献
Reddy, R. Buchi; Mouli, G. V. P. Chandra; Reddy, Y. D.
Phosphorus and Sulfur and the Related Elements, 1988 , vol. 40, p. 173 - 176
反应条件
1: 76 percent / SOCl2 / toluene
2: NH2OH*HCl, KOH / ethanol
3: Na2S2O4
View Scheme
参考文献
Gieren, Alfred; Betz, Helmut; Huebner, Thomas; Lamm, Viktor; Neidlein, Richard; Droste, Dao
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 4 p. 485 - 496
反应条件
1: NH3 / ethane-1,2-diol / 180 - 200 °C
2: aq. NaHS / Heating
View Scheme
参考文献
Pesin,V.G. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 186 - 188
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, # 2 p. 249 - 253
