溴乙醛合成路线 - 魔法化学

参考文献

Tschitschibabin; Schtschukina
Chemische Berichte, 1929 , vol. 62, p. 1075
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1929 , vol. 61, p. 1645

7664-41-7氨气+

17157-48-1溴乙醛

290-37-9吡嗪

参考文献

Tschitschibabin; Schtschukina
Chemische Berichte, 1929 , vol. 62, p. 1075
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1929 , vol. 61, p. 1645

5469-69-23-氨基-6-氯哒嗪+

17157-48-1溴乙醛

6775-78-66-氯咪唑并[1,2-b]哒嗪

参考文献

SUPERGEN, INC.
Patent: WO2008/58126 A2, 2008 ;
Location in patent: Page/Page column 49; 60 ;

6863-73-62-氨基-3-氯吡嗪+

17157-48-1溴乙醛

69214-33-18-氯咪唑并[1,2-a]吡嗪

参考文献

Macleod, Angus M.; Mitchell, Dale R.; Palmer, Nicholas J.; Van De Poel, Herve; Conrath, Katja; Andrews, Martin; Leyssen, Pieter; Neyts, Johan
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 585 - 589

6863-73-62-氨基-3-氯吡嗪+

17157-48-1溴乙醛

69214-33-18-氯咪唑并[1,2-a]吡嗪+

69214-34-28-溴咪唑并[1,2-a]吡嗪+

937790-53-9

参考文献

Schering Corporation
Patent: US2007/105864 A1, 2007 ;
Location in patent: Page/Page column 121 ;
US 20070105864 A1

24241-18-72-氨基-3,5-二溴吡嗪+

17157-48-1溴乙醛

63744-22-96,8-二溴咪唑并[1,2-a]吡嗪

参考文献

Bouloc, Nathalie; Large, Jonathan M.; Kosmopoulou, Magda; Sun, Chongbo; Faisal, Amir; Matteucci, Mizio; Reynisson, Johannes; Brown, Nathan; Atrash, Butrus; Blagg, Julian; McDonald, Edward; Linardopoulos, Spiros; Bayliss, Richard; Bavetsias, Vassilios
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 20 p. 5988 - 5993

38875-53-52,3-二氨基-5-溴吡啶+

17157-48-1溴乙醛

676371-00-96-溴-1H-咪唑并[1,2-a]吡啶-8-胺

参考文献

Dwyer, Michael P.; Paruch, Kamil; Alvarez, Carmen; Doll, Ronald J.; Keertikar, Kerry; Duca, Jose; Fischmann, Thierry O.; Hruza, Alan; Madison, Vincent; Lees, Emma; Parry, David; Seghezzi, Wolfgang; Sgambellone, Nicole; Shanahan, Frances; Wiswell, Derek; Guzi, Timothy J.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6216 - 6219

3829-80-92-氨基-4-甲基噻唑-5-甲酸甲酯+

17157-48-1溴乙醛

1017273-35-63-甲基-咪唑并[2,1-b]噻唑-2-羧酸甲酯

参考文献

ACTELION PHARMACEUTICALS LTD
Patent: WO2008/81399 A2, 2008 ;
Location in patent: Page/Page column 66 ;
WO 2008/081399 A2

6950-84-11-萘基脲+

17157-48-1溴乙醛

100381-97-3N-萘-1-基-1,3-恶唑-2-胺

参考文献

Bulletin de la Societe Chimique de France, , p. 2052 - 2061

98021-37-56-氨基-3-哒嗪甲酰胺+

17157-48-1溴乙醛

159045-50-8咪唑并[1,2-b]哒嗪-6-甲酰胺

参考文献

Ishikawa; Iizawa; Okonogi; Miyake
Journal of Antibiotics, 2000 , vol. 53, # 10 p. 1053 - 1070