1-氧杂环十四烷-2-酮合成路线 （共 44 条）
反应条件
1: 2N HCl / tetrahydrofuran / 3 h / 60 °C
2: oxygen, Sensitox (Rose Bengal polymer) / CH2Cl2 / 0.5 h / Irradiation
3: 75 percent / p-toluenesulfonic acid / benzene / 24 h / Heating
View Scheme
参考文献
Wasserman, Harry H.; Gambale, Ronald J.; Pulwer, Mitchell J.
Tetrahedron Letters, 1981 , vol. 22, # 18 p. 1737 - 1740
反应条件
1: 68 percent / 47percent HBr / toluene / Heating
2: 94 percent / NaI / acetone / Ambient temperature
3: 83 percent / p-TolSO3H / benzene / Heating
4: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation; var. solvents, var. conditions, other hydrides
View Scheme
参考文献
Abe, Motoji; Hayashikoshi, Takaoki; Kurata, Takeo
Chemistry Letters, 1994 , # 10 p. 1789 - 1792
反应条件
1: 94 percent / NaI / acetone / Ambient temperature
2: 83 percent / p-TolSO3H / benzene / Heating
3: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation; var. solvents, var. conditions, other hydrides
View Scheme
参考文献
Abe, Motoji; Hayashikoshi, Takaoki; Kurata, Takeo
Chemistry Letters, 1994 , # 10 p. 1789 - 1792
反应条件
1: 83 percent / p-TolSO3H / benzene / Heating
2: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation; var. solvents, var. conditions, other hydrides
View Scheme
参考文献
Abe, Motoji; Hayashikoshi, Takaoki; Kurata, Takeo
Chemistry Letters, 1994 , # 10 p. 1789 - 1792
反应条件
sodium cyanoborohydride in methanol
3 h; Ambient temperatureIrradiation;
参考文献
Abe, Motoji; Hayashikoshi, Takaoki; Kurata, Takeo
Chemistry Letters, 1994 , # 10 p. 1789 - 1792
反应条件
1: ozone / ethanol; cyclohexane / 8 h / 0 - 5 °C / |Inert atmosphere
2: sodium tetrahydroborate / methanol / 0 °C / |Inert atmosphere
3: 1H-imidazole / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
4: trifluoromethylsulfonic anhydride; water / dichloromethane / |Inert atmosphere
View Scheme
参考文献
Valerio, Viviana; Petkova, Desislava; Madelaine, Claire; Maulide, Nuno
Chemistry - A European Journal, 2013 , vol. 19, # 8 p. 2606 - 2610
反应条件
1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
2: trifluoromethylsulfonic anhydride; water / dichloromethane / |Inert atmosphere
View Scheme
参考文献
Valerio, Viviana; Petkova, Desislava; Madelaine, Claire; Maulide, Nuno
Chemistry - A European Journal, 2013 , vol. 19, # 8 p. 2606 - 2610
反应条件
trifluoromethylsulfonic anhydride; water in dichloromethane
Inert atmosphere;
参考文献
Valerio, Viviana; Petkova, Desislava; Madelaine, Claire; Maulide, Nuno
Chemistry - A European Journal, 2013 , vol. 19, # 8 p. 2606 - 2610
反应条件
in benzene
T=40°C; 72 h; Lipase P;
参考文献
Makita, Atushi; Nihira, Takuya; Yamada, Yasuhiro
Tetrahedron Letters, 1987 , vol. 28, # 7 p. 805 - 808
参考文献
Wiberg, Kenneth B.; Waldron, Roy F.
Journal of the American Chemical Society, 1991 , vol. 113, # 20 p. 7697 - 7705
