2-(4-羟基亚苄基)-丙二酸二乙酯合成路线 （共 6 条）
反应条件
aluminum oxide T=120°C; Knoevenagel condensation; microwave irradiation;
参考文献
Kidwai, Mazaahir; Sapra, Pooja; Bhushan, Kumar Ranjan
Journal of the Indian Chemical Society, 2002 , vol. 79, # 7 p. 596 - 598
反应条件
acetic acid in benzene
参考文献
Schehlmann, Volker; Berg-schultz, Katja
Patent: US2009/291107 A1, 2009 ;
反应条件
bentonite Actisil FF 0.25 h; Irradiation;
参考文献
Delgado; Tamariz; Zepeda; Landa; Miranda; Garcia
Synthetic Communications, 1995 , vol. 25, # 5 p. 753 - 759
反应条件
potassium carbonate in ethanol T=100°C; 0.166667 h; Microwave irradiationSealed tube;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 20 p. 5497 - 5502
反应条件
1: H2SO4 / -5 °C / anschliessend mit konz. wss. HNO3 bei -15grad behandeln 2: methanesulfonyl chloride; pyridine / Reaktion ueber 2 Stufen View Scheme
参考文献
Meltzer et al.
Journal of Organic Chemistry, 1957 , vol. 22, p. 1577,1580
反应条件
1: H2SO4 / -5 °C / anschliessend mit konz. wss. HNO3 bei -15grad behandeln
2: methanesulfonyl chloride; pyridine / Reaktion ueber 2 Stufen
3: palladium/charcoal; acetic acid / Hydrogenation
4: NaNO2; H2SO4; acetic acid / Behandeln der Bis-diazoniumsalz-Loesung mit NaI, Jod und Harnstoff in H2O und CHCl3
5: aqueous HI; acetic acid
View Scheme
参考文献
Meltzer et al.
Journal of Organic Chemistry, 1957 , vol. 22, p. 1577,1580
