molecular sieve; tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide in dichloromethane T=0 - 20°C; 4 h;

1: 2-bromo-6-(N,N-dimethylamino)naphthalene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane Inert atmosphere;

1.1: sodium disulfite / water / 145 °C / Inert atmosphere; sealed tube 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 2.2: Inert atmosphere View Scheme

water; mercury dichloride T=24°C; pH=7.4; aq. buffer;