(R)-1-((5-氨基-6-氯嘧啶-4-基)氨基)-2-丙醇合成路线 (共 5 条)
反应条件
TEA in butan-1-ol Heating;
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
反应条件
1: 86 percent / conc. HCl / Ambient temperature 2: 91 percent / NH3 / 65 °C 3: 44 percent / NaH / dimethylformamide / 0 - 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 31 p. 7420 - 7421
反应条件
hydrogenchloride Ambient temperature;
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
反应条件
1: 86 percent / conc. HCl / Ambient temperature 2: 91 percent / NH3 / 65 °C 3: 44 percent / NaH / dimethylformamide / 0 - 20 °C 4: 1.) TMSBr, 2.) H2O / 1.) MeCN, RT, 2.) acetone, 4 deg C View Scheme
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
反应条件
1: 86 percent / conc. HCl / Ambient temperature 2: 91 percent / NH3 / 65 °C View Scheme
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421