5,6-二氢-4H-1,3-二噻英-2-硫酮合成路线 （共 30 条）
反应条件
potassium hydroxide; dimethyl sulfoxide
T=0°C;
参考文献
Ram, Vishnu J.; Nath, Mahendra; Shukla
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 16 p. 2137 - 2140
反应条件
potassium hydroxide; dimethyl sulfoxide
T=0°C;
参考文献
Ram, Vishnu J.; Nath, Mahendra; Shukla
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 16 p. 2137 - 2140
反应条件
n-butyllithium
1.) THF, -5-(-10) grad C, 30 min, nitrogen, 2.) THF, 1 h at -5-(-10) grad C then 24 h at room temp.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tanimoto, Shigeo; Oida, Tatuo; Hatanaka, Kouhei; Sugimoto, Toyonari
Tetrahedron Letters, 1981 , vol. 22, p. 655 - 658
反应条件
n-butyllithium; thionyl chloride
1.) hexane, THF, -78 deg C, 5 min, 2.) hexane, THF, -78 deg C; Yield given. Multistep reaction;
参考文献
Oae, Shigeru; Inubushi, Yoichi; Yoshihara, Masakuni
Phosphorus, Sulfur and Silicon and the Related Elements, 1995 , vol. 103, # 1-4 p. 101 - 110
反应条件
1) K
1) DMF, -5 - 0 deg C, 2) MeOH; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hartke, Klaus; Kissel, Thomas; Quante, Josef; Matusch, Rudolf
Chemische Berichte, 1980 , vol. 113, # 5 p. 1898 - 1906
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; 1-cyanomethylimidazole
1.) CH2Cl2, H2O, 1 h, 2.) CH2Cl2, H2O, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ram, Vishnu J.; Singh, Sunil K.; Nath, Mahendra; Srivastava, Pratibha
Journal of Chemical Research - Part S, 1996 , # 1 p. 64 - 65
反应条件
potassium hydroxide
1.) DMSO, 0 deg C, 1 h, 2.) DMSO, overnight; Multistep reaction;
参考文献
Ram, Vishnu J.; Singh, Sunil K.; Nath, Mahendra; Srivastava, Pratibha
Journal of Chemical Research - Part S, 1996 , # 1 p. 64 - 65
反应条件
potassium hydroxide
1.) DMSO, 0 deg C, 1 h, 2.) DMSO, overnight; Multistep reaction;
参考文献
Ram, Vishnu J.; Singh, Sunil K.; Nath, Mahendra; Srivastava, Pratibha
Journal of Chemical Research - Part S, 1996 , # 1 p. 64 - 65
参考文献
Mills; Saunders
Journal of the Chemical Society, 1931 , p. 537,543
参考文献
Hanefeld
Archiv der Pharmazie, 1977 , vol. 310, # 6 p. 460 - 468
