4-苯基-3-丁烯-2-醇合成路线 （共 15 条）
反应条件
1.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 2 h / 0 - 20 °C 2.1: 1,2-dichloro-benzene / 24 h / |Reflux 2.2: 24 h / 20 °C View Scheme
参考文献
Hou, Shili; Li, Xinyao; Xu, Jiaxi
Journal of Organic Chemistry, 2012 , vol. 77, # 23 p. 10856 - 10869
反应条件
T=500°C; P=0.01 Torr;
参考文献
Al-Etaibi, Alya M.; Al-Awadi, Nouria A.; Ibrahim, Maher R.; Ibrahim, Yehia A.
Molecules, 2010 , vol. 15, # 1 p. 407 - 419
反应条件
1: With tetrahydropyrrolo[2,1-c][1,2,4]triazole carbene; (Ph)2SiH2 in N,N-dimethyl-formamide; mineral oil T=20°C; 6 h; Inert atmosphere; 2: With tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide; mineral oil T=20°C; 0.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhao, Qiwu; Curran, Dennis P.; Malacria, Max; Fensterbank, Louis; Goddard, Jean-Philippe; Lacote, Emmanuel
Chemistry - A European Journal, 2011 , vol. 17, # 36 p. 9911 - 9914
反应条件
dichloro(.eta.3:.eta.2:.eta.3-dodeca-2,6,10-triene-1,12-diyl)ruthenium(IV); caesium carbonate; isopropyl alcohol T=82°C; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Cadierno, Victorio; Crochet, Pascale; Francos, Javier; Garcia-Garrido, Sergio E.; Gimeno, Jose; Nebra, Noel
Green Chemistry, 2009 , vol. 11, # 12 p. 1992 - 2000
反应条件
palladium dichloride in methanol T=40°C; 18 h; Inert atmosphereGreen chemistry; chemoselective reaction;
参考文献
Wang, Hu; Li, Li; Bai, Xing-Feng; Shang, Jun-Yan; Yang, Ke-Fang; Xu, Li-Wen
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 2-3 p. 341 - 347
参考文献
Klages
Chemische Berichte, 1906 , vol. 39, p. 2589
反应条件
tert-butyl 1-hydroxy-2-methyl-6-trifluoromethyl-1H-indole-3-carboxylate; oxygen; copper(l) chloride in N,N-dimethyl-formamide T=50°C; P=760.051 Torr; 8 h; chemoselective reaction;
参考文献
Shen, Shu-Su; Kartika, Vita; Tan, Ying Shan; Webster, Richard D.; Narasaka, Koichi
Tetrahedron Letters, 2012 , vol. 53, # 8 p. 986 - 990
反应条件
1: With titanium(IV) isopropylate in chloroform T=20°C; 1 h; Molecular sieve; 2: With tert.-butylhydroperoxide in chloroform; toluene T=-20°C; Sharpless epoxidation; 4 h; chemoselective reaction;
参考文献
Shei, Chun-Tin; Chien, Hao-Lun; Sung, Kuangsen
Synlett, 2008 , # 7 p. 1021 - 1026
反应条件
1: With chromium(VI) oxide; aluminum oxide; tert-butyl alcohol 0.166667 h; 2: With hydroxylamine hydrochloride 0.116667 h;
参考文献
Kiasat, Ali Reza; Kazemi, Foad; Nourbakhsh, Kazem
Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 9 p. 1809 - 1812
反应条件
acetonitrile dicarbonyl(1,3-bis(trimethylsilyl)-4,5,6,7-tetrahydro-2H-inden-2-one)iron; acetone T=90°C; Opppenauer oxidation; 18 h; Inert atmosphere;
参考文献
Plank, Taylor N.; Drake, Jessica L.; Kim, Daniel K.; Funk, Timothy W.
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 597 - 601
