2-(乙酰氧基)-苯甲酸 3-[(硝基氧基)甲基]苯基酯合成路线 （共 4 条）
反应条件
nitric acid; acetic anhydride in dichloromethane T=0 - 20°C; 2 h;
参考文献
Nicox S.A.
Patent: US6696591 B1, 2004 ;
Location in patent: Page column 5-6 ;
反应条件
1: SOCl2; pyridine / CH2Cl2 / 2 h / 0 °C 2: Et3N / CH2Cl2 / 0 °C 3: NaBH4 / tetrahydrofuran / 0 °C 4: SOCl2; pyridine / CH2Cl2 / -30 - 20 °C 5: AgNO3 / acetonitrile / Heating View Scheme
参考文献
Chiroli, Valerio; Benedini, Francesca; Ongini, Ennio; Del Soldato, Piero
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 4 p. 441 - 446
反应条件
1: NaBH4 / tetrahydrofuran / 0 °C 2: SOCl2; pyridine / CH2Cl2 / -30 - 20 °C 3: AgNO3 / acetonitrile / Heating View Scheme
参考文献
Chiroli, Valerio; Benedini, Francesca; Ongini, Ennio; Del Soldato, Piero
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 4 p. 441 - 446
反应条件
1: Et3N / CH2Cl2 / 0 °C 2: NaBH4 / tetrahydrofuran / 0 °C 3: SOCl2; pyridine / CH2Cl2 / -30 - 20 °C 4: AgNO3 / acetonitrile / Heating View Scheme
参考文献
Chiroli, Valerio; Benedini, Francesca; Ongini, Ennio; Del Soldato, Piero
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 4 p. 441 - 446
