1,4-二硫杂螺[4.5]癸烷合成路线 （共 34 条）
反应条件
bis(acetylacetonate)nickel(II); P(t-Bu)2Me in diethyl ether; toluene 20 h; Heating;
参考文献
Huang, Li-Fu; Huang, Chih-Hao; Stulgies, Baldur; De Meijere, Armin; Luh, Tien-Yau
Organic Letters, 2003 , vol. 5, # 23 p. 4489 - 4491
反应条件
1: sulphuryl chloride / CCl4 / 1 h / 0 °C 2: 1.) triethylamine, 2.) silica gel (Merk Kieselgel H, type 60), water / 1.) CCl4, 0 deg C -> room temperature View Scheme
参考文献
Bulman-Page, Philip C.; Ley, Steven V.; Morton, Judith A.; Williams, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 457 - 461
反应条件
tetraethylammonium bromide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in chloroform T=20°C; 0.75 h;
参考文献
Shukla, Vidyanand G.; Salgaonkar, Paresh D.; Akamanchi, Krishnacharya G.
Synlett, 2005 , # 9 art. no. D39404ST, p. 1483 - 1485
反应条件
2,2'-azo-bisisobutyronitrile in neat (no solvent) T=80°C; 1.5 h; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 45, # 17 p. 3393 - 3395
反应条件
2,2'-azo-bisisobutyronitrile in neat (no solvent) T=80°C; 1.1 h; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 45, # 17 p. 3393 - 3395
反应条件
bromine in chloroform 0.833333 h; Ambient temperatureother substituted cyclohexanone ethanediyl S,S-acetals; different ratio of Br2:substrate; Mechanism;
参考文献
Tetrahedron, , vol. 47, # 24 p. 4187 - 4194
反应条件
aluminium trichloride; borane-pyridine complex in dichloromethane 0.0833333 h;
参考文献
Kikugawa, Yasuo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 609 - 610
反应条件
n-butyllithium in diethyl ether T=25°C; 6 h;
参考文献
Wilson, Stephen R.; Georgiadis, Gregory M.; Khatri, Hiralal N.; Bartmess, John E.
Journal of the American Chemical Society, 1980 , vol. 102, # 10 p. 3577 - 3583
反应条件
bis(acetylacetonate)nickel(II); P(t-Bu)2Me in diethyl ether; toluene
20 h; Heating;
参考文献
Huang, Li-Fu; Huang, Chih-Hao; Stulgies, Baldur; De Meijere, Armin; Luh, Tien-Yau
Organic Letters, 2003 , vol. 5, # 23 p. 4489 - 4491
反应条件
(i), (ii) (alkaline hydrolysis); Multistep reaction;
参考文献
Oishi,T. et al.
Tetrahedron Letters, 1972 , p. 1085 - 1088
