1,6-二溴-2-羟基萘-3-羧酸合成路线 （共 10 条）
反应条件
bromine; acetic acid T=20 - 125°C; 10 h;
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
Location in patent: Paragraph 0051; 0052 ;
反应条件
bromine; acetic acid
参考文献
Chemische Berichte, , vol. 58, p. 2850
反应条件
bromine; acetic acid
参考文献
Journal of the Indian Chemical Society, , vol. 25, p. 43,44
参考文献
Journal of the Indian Chemical Society, , vol. 25, p. 43,44
参考文献
Journal of the Indian Chemical Society, , vol. 25, p. 485
参考文献
Chemische Berichte, , vol. 58, p. 2850
参考文献
Journal of the Indian Chemical Society, , vol. 25, p. 43,44
反应条件
potassium carbonate in acetone T=60°C; 10 h;
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
Location in patent: Paragraph 0055; 0056; 0119; 0120 ;
反应条件
hydrogenchloride; tin in acetic acid T=125°C; 12 h; Reflux;
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
Location in patent: Paragraph 0053; 0054 ;
反应条件
1: bromine
2: aqueous nitric acid
3: 220 °C
View Scheme
参考文献
Fries; Schimmelschmidt
Justus Liebigs Annalen der Chemie, 1930 , vol. 484, p. 245,271
