3-(甲基氨基)-4-硝基吡啶 1-氧化合成路线 （共 5 条）
反应条件
hydrogen; nickel in methanol
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2005/44793 A2, 2005 ;
Location in patent: Page/Page column 239 ;
WO 2005/044793 A2
反应条件
1: H2 / 5percent Pd/C / ethanol
2: 44 percent / 4 h / 110 °C
View Scheme
参考文献
Katner; Brown
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 563 - 566
反应条件
1: reducing agent <H>
View Scheme
参考文献
Yano, Yumihiko; Yatsu, Isao; Oya, Eiichi; Ohshima, Masashi
Chemistry Letters, 1983 , p. 775 - 778
反应条件
iron
T=180°C; 0.5 h; Microwave irradiation;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/12622 A2, 2008 ;
Location in patent: Page/Page column 59 ;
WO 2008/012622 A2
反应条件
1: H2 / 5percent Pd/C / ethanol
2: 10 percent / 20 h / 120 °C
View Scheme
参考文献
Katner; Brown
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 563 - 566
