1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 3: With hydrogenchloride in tetrahydrofuran; hexane T=0°C; 0.166667 h;

1.1: 97 percent / imidazole / dimethylformamide / 3 h 2.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.2: triisopropyl borate / tetrahydrofuran; hexane / -78 - 20 °C 2.3: 79 percent / aq. HCl / tetrahydrofuran; hexane / 0.17 h / 0 °C View Scheme

1.1: 97 percent / imidazole / dimethylformamide / 3 h 2.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.2: triisopropyl borate / tetrahydrofuran; hexane / -78 - 20 °C 2.3: 79 percent / aq. HCl / tetrahydrofuran; hexane / 0.17 h / 0 °C View Scheme