(R)-1-(6-氯-9H-嘌呤-9-基)-2-丙醇合成路线 （共 5 条）
反应条件
[Ru(II)(η6-benzene)(μ-Cl)Cl]2; sodium formate; (R)-(-)-α,α-diphenyl-2-pyrrolidinemethanol in acetonitrile T=20 - 30°C; 48 h; enantioselective reaction;
参考文献
Zhang, Qian; Ma, Bai-Wei; Wang, Qian-Qian; Wang, Xing-Xing; Hu, Xia; Xie, Ming-Sheng; Qu, Gui-Rong; Guo, Hai-Ming
Organic Letters, 2014 , vol. 16, # 7 p. 2014 - 2017
反应条件
hydrogenchloride Ambient temperature;
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
反应条件
1: 91 percent / NH3 / 65 °C 2: 44 percent / NaH / dimethylformamide / 0 - 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 31 p. 7420 - 7421
反应条件
1: 91 percent / NH3 / 65 °C 2: 44 percent / NaH / dimethylformamide / 0 - 20 °C 3: 1.) TMSBr, 2.) H2O / 1.) MeCN, RT, 2.) acetone, 4 deg C View Scheme
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
参考文献
Larrow, Jay F.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 1996 , vol. 118, # 31 p. 7420 - 7421
