4-溴-2-碘-6-硝基苯胺合成路线 （共 5 条）
反应条件
trifluorormethanesulfonic acid; IPy2BF4 in dichloromethane T=20°C; Iodination; 72 h;
参考文献
Ezquerra, Jesus; Pedregal, Concepcion; Lamas, Carlos; Barluenga, Jose; Perez, Marta; Garcia-Martin, Miguel Angel; Gonzalez, Jose M.
Journal of Organic Chemistry, 1996 , vol. 61, # 17 p. 5804 - 5812
反应条件
1: glacial acetic acid; sodium acetate / beim Bromieren 2: p-toluenesulfonic acid dichloroamide; glacial acetic acid; sodium iodide View Scheme
参考文献
Journal of the Chemical Society, , p. 783
参考文献
Journal of the Chemical Society, , p. 783
反应条件
1: With sulfuric acid T=0 - 5°C; 1 h; 2: With sodium nitrite T=0 - 5°C; 2 h; 3: With ethanol; copper(II) sulfate in water 2 h; Heating / reflux;
参考文献
PROLYSIS LTD.
Patent: WO2007/148093 A1, 2007 ;
Location in patent: Page/Page column 14-15 ;
WO 2007/148093 A1
反应条件
1: 89 percent / Et3N / Pd(PPh3)2Cl2-CuI / 3 h / 0 - 20 °C 2: 55 percent / CuI / dimethylformamide / 2.5 h / 100 °C View Scheme
参考文献
Ezquerra, Jesus; Pedregal, Concepcion; Lamas, Carlos; Barluenga, Jose; Perez, Marta; Garcia-Martin, Miguel Angel; Gonzalez, Jose M.
Journal of Organic Chemistry, 1996 , vol. 61, # 17 p. 5804 - 5812
