2,6-二氟苯甲酰氯合成路线

参考文献

Yang, Katherine S.; Budin, Ghyslain; Reiner, Thomas; Vinegoni, Claudio; Weissleder, Ralph
Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6598 - 6603

59489-71-32-氨基-5-溴吡嗪+

18063-02-02,6-二氟苯甲酰氯

1028700-78-8N-(5-溴-吡嗪-2-基)-2,6-二氟苯甲酰胺

参考文献

CalciMedica, Inc.
Patent: US2011/263612 A1, 2011 ;
Location in patent: Page/Page column 161 ;
US 20110263612 A1

18063-02-02,6-二氟苯甲酰氯+

105-53-3丙二酸二乙酯

13670-99-02,6-二氟苯乙酮

参考文献

WO2013/85686 A1, ;

Page/Page column 22 ;

6148-64-7丙二酸单乙酯钾盐+

18063-02-02,6-二氟苯甲酰氯

13670-99-02,6-二氟苯乙酮

参考文献

WO2013/85686 A1, ;

Page/Page column 23 ;

67-56-1甲醇+

18063-02-02,6-二氟苯甲酰氯

13671-00-62,6-二氟苯甲酸甲酯+

385-00-22,6-二氟苯甲酸

参考文献

Park, Kyoung-Ho; Kevill, Dennis N.
Journal of Physical Organic Chemistry, 2012 , vol. 25, # 3 p. 267 - 270

67-56-1甲醇+

18063-02-02,6-二氟苯甲酰氯

13671-00-62,6-二氟苯甲酸甲酯

参考文献

Park, Kyoung-Ho; Kevill, Dennis N.
Journal of Physical Organic Chemistry, 2012 , vol. 25, # 3 p. 267 - 270

95-54-51,2-苯二胺+

18063-02-02,6-二氟苯甲酰氯

164593-05-9

参考文献

Tarte, Naresh H.; Woo, Seong Ihl; Cui, Liqiang; Gong, Young-Dae; Hwang, Young Ho
Journal of Organometallic Chemistry, 2008 , vol. 693, # 4 p. 729 - 736

18063-02-02,6-二氟苯甲酰氯

164593-05-9

参考文献

Roth, Thomas; Morningstar, Marshall L.; Boyer, Paul L.; Hughes, Stephen H.; Buckheit Jr., Robert W.; Michejda, Christopher J.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 26 p. 4199 - 4207

18063-02-02,6-二氟苯甲酰氯

18063-03-12,6-二氟苯甲酰胺

参考文献

Journal of Medicinal Chemistry, , vol. 11, # 4 p. 814 - 819

18063-02-02,6-二氟苯甲酰氯

150368-37-92-氨基-6-氟-3-硝基苯甲酸乙酯

参考文献

Kyoung Soon Kim; Qian; Bird; Dickinson; Moreland; Schaeffer; Waldron; Delaney; Weller; Miller
Journal of Medicinal Chemistry, 1993 , vol. 36, # 16 p. 2335 - 2342