反应条件
1: phenylacetylene With isopropylmagnesium chloride in tetrahydrofuran
T=0 - 20°C; 1 h; Inert atmosphere;
2: (2,6-dimethyl-phenyl)-magnesium iodide With 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical in tetrahydrofuran
T=66°C; 2.5 h; Inert atmosphere;
3: With water; ammonium chloride in tetrahydrofuran; tert-butyl methyl ether
参考文献
Maji, Modhu Sudan; Murarka, Sandip; Studer, Armido
Organic Letters, 2010 , vol. 12, # 17 p. 3878 - 3881