(苯基氧代甲基)膦酸二甲酯合成路线 （共 52 条）
反应条件
1.) benzene, r.t., 12 h; 2.) benzene, 4 h, reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Breuer, Eli; Karaman, Rafik; Goldblum, Amiram; Leader, Haim
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 2029 - 2034
反应条件
1: aq. HCl / tetrahydrofuran
2: aq. Na2CO3
3: diethyl ether
View Scheme
参考文献
Seyferth,D. et al.
Journal of the American Chemical Society, 1967 , vol. 89, # 18 p. 4811 - 4812
反应条件
water
1.) ether, room temperature, 24 h; 2.) THF, room temperature, 3 h; Yield given. Multistep reaction;
参考文献
Sekine, Mitsuo; Satoh, Masaki; Yamagata, Hikaru; Hata, Tsujiaki
Journal of Organic Chemistry, 1980 , vol. 45, p. 4162 - 4167
反应条件
KCN-18-crown-6 complex in diethyl ether
Phospha-benzoin reaction;
参考文献
Smith, Austin G.; Johnson, Jeffrey S.
Organic Letters, 2010 , vol. 12, # 8 p. 1784 - 1787
反应条件
1: 98 percent / NaI / acetone / 12 h / Ambient temperature
2: 95 percent / conc. aq. hydrochloric acid
3: 74 percent / NaI / acetonitrile; acetone / 48 h / Heating
4: 1M aq. sodium hydroxide, sodium borohydride
View Scheme
参考文献
Karaman, Rafik; Goldblum, Amiram; Breuer, Eli; Leader, Haim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 765 - 774
反应条件
trimethylsilyl bromide in acetonitrile
3 h; Ambient temperature;
参考文献
Karaman, Rafik; Goldblum, Amiram; Breuer, Eli; Leader, Haim
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 765 - 774
参考文献
Kabatschnik; Rossiiskaja
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1945 , p. 597,600
Chem.Abstr., 1947 , p. 88
反应条件
water
1.) ether, room temperature, 24 h; 2.) THF, room temperature, 3 h; Yield given. Multistep reaction;
参考文献
Sekine, Mitsuo; Satoh, Masaki; Yamagata, Hikaru; Hata, Tsujiaki
Journal of Organic Chemistry, 1980 , vol. 45, p. 4162 - 4167
反应条件
1: With triethylaluminum in n-heptane; toluene
T=0°C; 0.166667 h; Inert atmosphere;
2: With water in n-heptane; toluene
Inert atmosphere;
参考文献
Seven, Ozlem; Polat-Cakir, Sidika; Hossain, Md. Shakhawoat; Emrullahoglu, Mustafa; Demir, Ayhan S.
Tetrahedron, 2011 , vol. 67, # 19 p. 3464 - 3469
参考文献
Kabatschnik; Rossiiskaja
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1945 , p. 364,371
Chem.Abstr., 1946 , p. 4688
