hydrogenchloride in methanol T=20°C; 48 h;

1.1: dicyclohexyl-carbodiimide / tetrahydrofuran / 0 °C / Inert atmosphere 2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere 2.2: 2 h / 0 - 20 °C / Inert atmosphere 3.1: ethanol; sodium / 24 h / 20 °C View Scheme

hydrogenchloride in methanol

magnesium diethoxide 1.) benzene, reflux, 2 h, 2.) benzene; Multistep reaction;

potassium hydroxide in methanol; water

triethylamine; trichlorophosphate T=60°C; 3 h;