1: Et3N / tetrahydrofuran 2: aq. OsO4, N-methylmorpholine-N-oxide / tetrahydrofuran; acetone / 24 h 3: TsOH / acetone / 18 h 4: 86 percent / aq. ceric ammonium nitrate / acetonitrile / 0.08 h / 0 °C 5: 78 percent / pyridinium chlorochromate, pyridine, molecular sieves / CH2Cl2 View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: (Ph₃P)4Pd / tetrahydrofuran / 12 h<br />2: via Pseudomonas cepacia catalyzed acetylation with isopropenyl acetate<br /> <br /> &nbsp;