1: aq. OsO4, N-methylmorpholine-N-oxide / tetrahydrofuran; acetone / 24 h 2: TsOH / acetone / 18 h 3: 86 percent / aq. ceric ammonium nitrate / acetonitrile / 0.08 h / 0 °C 4: 78 percent / pyridinium chlorochromate, pyridine, molecular sieves / CH2Cl2 View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: (Ph₃P)4Pd / tetrahydrofuran / 12 h<br />2: via Pseudomonas cepacia catalyzed acetylation with isopropenyl acetate<br />3: Et₃N / tetrahydrofuran<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />&nbsp;Yield given;&nbsp;<br /> &nbsp;