2-氨基-6-甲基吡啶合成路线 （共 244 条）
反应条件
1: tetrafluoroboric acid; sodium nitrite / water 2: potassium permanganate / water / Reflux 3: thionyl chloride 4: Pd-BaSO4; hydrogen View Scheme
参考文献
Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547
反应条件
1: With sulfuric acid; nitric acid T=20 - 55°C; 2 h; 2: With chloro-trimethyl-silane; tert.-butylnitrite in tetrachloromethane; dichloromethane Heating;
参考文献
Romines, Karen R.; Freeman, George A.; Schaller, Lee T.; Cowan, Jill R.; Gonzales, Steve S.; Tidwell, Jeffrey H.; Andrews III, Clarence W.; Stammers, David K.; Hazen, Richard J.; Ferris, Robert G.; Short, Steven A.; Chan, Joseph H.; Boone, Lawrence R.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 727 - 739
反应条件
T=550°C; Further byproducts given;
参考文献
Journal of Chemical Research, Miniprint, , # 12 p. 4935 - 4953
反应条件
T=550°C; Further byproducts given;
参考文献
Journal of Chemical Research, Miniprint, , # 12 p. 4935 - 4953
参考文献
Fukase, Koichi; Nakayama, Hideo; Kurosawa, Motohiro; Ikegaki, Toshiki; Kanoh, Takeshi; et al.
Journal of Carbohydrate Chemistry, 1994 , vol. 13, # 5 p. 715 - 736
反应条件
1: HBr; NaNO2 / -20 °C 2: CrO3 / H2SO4 View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: I2; H5IO6; H2SO4 / acetic acid; H2O / 80 °C 2: 61 percent / NaNO2; HCl / 20 °C View Scheme
参考文献
ZOETIS LLC; MENON, Sanjay; SHEEHAN, Susan M.K.; VAILLIANCOURT, Valerie A.
Patent: WO2014/39484 A1, 2014 ;
反应条件
1: 75 percent / conc. H2SO4, HNO3 / 4 h / 50 °C 2: 17 percent / conc. H2SO4, HNO3 / 5 h / 120 °C View Scheme
参考文献
Ritter, H.; Licht, H. H.
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 2 p. 585 - 590
反应条件
1: 77 percent / toluene / 95 °C 2: 32 percent / aq. NaOH; KMnO4 / 0.5 h / Heating View Scheme
参考文献
Kelly, T. Ross; Lang, Fengrui
Journal of Organic Chemistry, 1996 , vol. 61, # 14 p. 4623 - 4633
反应条件
1: 2: With potassium permanganate; water T=75°C;
参考文献
Ulrich, Sebastien; Petitjean, Anne; Lehn, Jean-Marie
European Journal of Inorganic Chemistry, 2010 , # 13 p. 1913 - 1928
