2-氨基-6-甲基吡啶合成路线 （共 244 条）
反应条件
1: 0 °C
2: aq. sodium hydroxyde
3: 66 percent / cc. sulfuric acid / H2O / 3 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
1: 0 °C
2: aq. sodium hydroxyde
3: 60 percent / cc. sulfuric acid, sodium sulfite / H2O / 5 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
1: 0 °C
2: aq. sodium hydroxyde
3: 65 percent / cc. sulfuric acid, sodium sulfite / H2O / 5 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
1: 0 °C
2: aq. sodium hydroxyde
3: 52 percent / dil. sulfuric acid / H2O / 3 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
1.1: HBr; Br2 / H2O / 0.83 h / -20 °C
1.2: NaNO2 / H2O / 2.5 h / -20 °C
2.1: 88 percent / N-bromosuccinimide; benzoylperoxide / CCl4 / 4 h / Heating
View Scheme
参考文献
Mandal, Ashis Baran; Augustine, John Kallikat; Quattropani, Anna; Bombrun, Agnes
Tetrahedron Letters, 2005 , vol. 46, # 36 p. 6033 - 6036
反应条件
in ethanol
0.166667 h; Heating;
参考文献
Mitchell, James A.; Reid, David H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 499 - 507
反应条件
1: 41 percent / 220 °C
2: 83 percent / 85percent hydrazin hydrate / methanol / 15 h / Heating
View Scheme
参考文献
Bautista, Dorothy V.; Dewan, John C.; Thompson, Laurence K.
Canadian Journal of Chemistry, 1982 , vol. 60, p. 2583 - 2593
反应条件
1: 95 percent / 1 h / 190 °C
2: N-bromosuccinimide; AIBN / benzene / 5 h / Heating
View Scheme
参考文献
Keenan, Richard M.; Miller, William H.; Barton, Linda S.; Bondinell, William E.; Cousins, Russell D.; Eppley, Daniel F.; Hwang, Shing-Mei; Kwon, Chet; Lago, M. Amparo; Nguyen, Thomas T.; Smith, Brian R.; Uzinskas, Irene N.; Yuan, Catherine C. K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 13 p. 1801 - 1806
反应条件
1: concentrated H2SO4; concentrated HNO3
2: acetic acid; bromine
3: sodium nitrite; concentrated aqueous hydrochloric acid / Diazotization
View Scheme
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
1: concentrated H2SO4; concentrated HNO3
2: acetic acid; bromine
3: sodium nitrite; concentrated aqueous hydrochloric acid / Diazotization
View Scheme
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
