2-氨基-6-甲基吡啶合成路线 （共 244 条）
反应条件
in 1,4-dioxane
24 h; Ambient temperature;
参考文献
Sudha, L. V.; Sathyanarayana, D. N.
Journal of Molecular Structure, 1985 , vol. 131, p. 141 - 146
反应条件
triethylamine in dichloromethane
参考文献
Ghosh, Kumaresh; Sen, Tanushree; Froehlich, Roland
Tetrahedron Letters, 2007 , vol. 48, # 36 p. 6308 - 6311
反应条件
potassium carbonate in dichloromethane
参考文献
Goswami, Shyamaprosad; Ghosh, Kumaresh; Mukherjee, Reshmi
Journal of the Indian Chemical Society, 1999 , vol. 76, # 11-12 p. 661 - 664
参考文献
Bergeron, Philippe; Farthing, Christopher N.; Jones, Stuart D.; Liebeschuetz, John W.; Lively, Sarah E.; McGee, Lawrence R.; McKendry, Sharon; Sheppard, David; Young, Stephen C.
Patent: US2006/84802 A1, 2006 ;
Location in patent: Page/Page column 30 ;
US 20060084802 A1
反应条件
1.1: HBr; bromine / 2 h / -20 °C
1.2: 77 percent / sodium nitrite / H2O / 1.75 h / -20 - 15 °C
2.1: 50 percent / sodium formate; benzyltriethylammonium chloride; NaOH / Pd/C / H2O / 216 h / Heating
3.1: N-bromosuccinimide / CCl4 / 0.5 h / Heating
3.2: 21 percent / benzoyl peroxide / CCl4 / Heating
View Scheme
参考文献
Voegtle, Fritz; Hochberg, Robert; Kochendoerfer, Frank; Windscheif, Paul-Michael; Volkmann, Martin; Jansen, Martin
Chemische Berichte, 1990 , vol. 123, # 11 p. 2181 - 2185
反应条件
in acetone
3 h; Reflux;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; RENSLO, Adam R.; GALLARDO-GODOY, Alejandra; SILBER, B. Michael; PRUSINER, Stanley B.; GILES, Kurt; LI, Zhe; NEITZ, R. Jeffrey
Patent: WO2013/33037 A2, 2013 ;
Location in patent: Paragraph 0752 ;
反应条件
in acetonitrile
4 - 8 h; Reflux;
参考文献
Adhami, Forogh; Safavi, Maliheh; Ehsani, Maryam; Ardestani, Sussan K.; Emmerling, Franziska; Simyari, Farzaneh
Dalton Transactions, 2014 , vol. 43, # 21 p. 7945 - 7957
反应条件
in acetone
0.5 h; Reflux;
参考文献
Treder, Adam P.; Andruszkiewicz, Ryszard; Zgoda, Wlodzimierz; Walkowiak, Aleksandra; Ford, Celeste; Hudson, Alan L.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 1 p. 156 - 167
反应条件
sodium tetrahydroborate in methanol
T=20°C; Condensation; hydrogenation; 48 h;
参考文献
Ferrarini, Pier Luigi; Mori, Claudio; Badawneh, Muwaffag; Calderone, Vincenzo; Greco, Rosamiria; Manera, Clementina; Martinelli, Adriano; Nieri, Paola; Saccomanni, Giuseppe
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 9 p. 815 - 826
反应条件
1: ethanol / 5 h / 20 °C
2: NaBH4 / tetrahydrofuran / 8 h / Heating
View Scheme
参考文献
Lindstroem, Stefan; Ahmad, Tania; Grivas, Spiros
Heterocycles, 1994 , vol. 38, # 3 p. 529 - 540
