2-氨基-6-甲基吡啶合成路线 （共 244 条）
参考文献
Merck and Co., Inc.
Patent: US4144341 A1, 1979 ;
反应条件
in tetrahydrofuran; pyridine
T=20°C; 12 h;
参考文献
Sun, Wen-Hua; Zhang, Wen; Gao, Tielong; Tang, Xiubo; Chen, Liyi; Li, Yan; Jin, Xianglin
Journal of Organometallic Chemistry, 2004 , vol. 689, # 5 p. 917 - 929
反应条件
copper(l) iodide in N,N-dimethyl-formamide
T=80°C; 24 h; Green chemistry;
参考文献
Yang, Sizhuo; Yan, Hao; Ren, Xiaoyu; Shi, Xiaokang; Li, Jian; Wang, Yuling; Huang, Guosheng
Tetrahedron, 2013 , vol. 69, # 31 p. 6431 - 6435
反应条件
1: aqueous hydrobromic acid / Behandeln mit Brom und mit wss. Natriumnitrit-Loesung
2: 200 °C
3: water; hydrogen peroxide / unter Kuehlung
View Scheme
参考文献
Clemo et al.
Journal of the Chemical Society, 1954 , p. 2693,2697
参考文献
Bristol-Myers Squibb Company
Patent: US2008/107624 A1, 2008 ;
Location in patent: Page/Page column 48 ;
反应条件
PPA
T=100°C; Condensation; 4 h;
参考文献
Ferrarini, Pier Luigi; Mori, Claudio; Manera, Clementina; Mori, Filippo; Calderone, Vincenzo; Martinotti, Enrica
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 5 p. 1123 - 1127
反应条件
sulfur in ethanol
24 h; Heating;
参考文献
Sudha, L. V.; Manogaran, S.; Sathyanarayana, D. N.
Magnetic Resonance in Chemistry, 1985 , vol. 23, # 7 p. 591 - 596
参考文献
Feist; Kuklinski
Archiv der Pharmazie (Weinheim, Germany), 1936 , vol. 274, p. 425,435
反应条件
in ethanol
3 h; Heating;
参考文献
Hassan, Hoda Y.; El-Koussi, Nawal A.; Farghaly, Zeinab S.
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 5 p. 863 - 866
反应条件
1: 0 °C
2: aq. sodium hydroxyde
3: 62 percent / dil. sulfuric acid / H2O / 4 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
