2-氨基-6-甲基吡啶合成路线 （共 244 条）
参考文献
Willink; Wibaut
Recueil des Travaux Chimiques des Pays-Bas, 1934 , vol. 53, p. 417,420
反应条件
1: 82 percent / NaNO2, Br2, 48percent HBr / 5 °C 2: 53 percent / KMnO4 / H2O / Heating 3: 1) NEt3, ethyl chloroformate, 2) LiAlH4 / 1) benzene, rt, 1 h, 2) THF, -78 deg C, 30 min View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 9 p. 2446 - 2458
反应条件
1.1: HBr; Br2 / H2O / 0.83 h / -20 °C 1.2: NaNO2 / H2O / 2.5 h / -20 °C 2.1: 88 percent / N-bromosuccinimide; benzoylperoxide / CCl4 / 4 h / Heating 3.1: 86 percent / CaCO3 / H2O / 8 h / Heating View Scheme
参考文献
Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
反应条件
1: concentrated H2SO4; concentrated HNO3 2: sodium nitrite; aqueous hydrochloric acid / Diazotization View Scheme
参考文献
Beijing Yiling Bioengineering Co., Ltd.
Patent: EP2366691 A1, 2011 ;
反应条件
T=550°C; Further byproducts given;
参考文献
Journal of Chemical Research, Miniprint, , # 12 p. 4935 - 4953
反应条件
T=550°C; Further byproducts given;
参考文献
Journal of Chemical Research, Miniprint, , # 12 p. 4935 - 4953
反应条件
1: sodium nitrite; aqueous tetrafluoroboric acid 2: H2O; KMnO4 View Scheme
参考文献
Roe et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 4152
反应条件
1: concentrated H2SO4; concentrated HNO3 2: sodium nitrite; aqueous hydrochloric acid / Diazotization 3: platinum; palladium/BaCO3; ethyl acetate / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 69, p. 63,66
反应条件
1: concentrated H2SO4; concentrated HNO3 2: sodium nitrite; aqueous hydrochloric acid / Diazotization 3: SnCl2; concentrated aqueous HCl View Scheme
参考文献
Parker; Shive
Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
反应条件
1: 26 percent / H2SO4, HNO3 / 80 °C 2: 97 percent / H2 / 10 percent Pd/C / methanol View Scheme
参考文献
Ohmori; Kubota; Shimizu-Sasamata; Okada; Sakamoto
Journal of Medicinal Chemistry, 1996 , vol. 39, # 6 p. 1331 - 1338
