2-氨基-6-甲基吡啶合成路线 (共 244 条)
反应条件
N-iodo-succinimide; acetic acid in benzene T=20°C; 72 h; regioselective reaction;
参考文献
Synlett, , # 2 p. 208 - 214
反应条件
potassium tert-butylate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; tris(dibenzylideneacetone)dipalladium (0) in toluene T=90°C;
参考文献
Tetrahedron Letters, , vol. 49, # 21 p. 3471 - 3474
反应条件
3-(diphenyl-phosphino)propane; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) in toluene T=80°C;
参考文献
Journal of Organometallic Chemistry, , vol. 622, # 1-2 p. 6 - 18
反应条件
phosgene; isopropyl-benzene
参考文献
DE479282 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2647
反应条件
hydrogenchloride Diazotization;
参考文献
Lacer, S.A.
Patent: US4614833 A1, 1986 ;
反应条件
sulfuric acid; nitric acid 2 h; Ambient temperature;
参考文献
Ohmori; Kubota; Shimizu-Sasamata; Okada; Sakamoto
Journal of Medicinal Chemistry, 1996 , vol. 39, # 6 p. 1331 - 1338
反应条件
sodium hydroxide; Concentrated HNO3
参考文献
SmithKline Beecham Corporation
Patent: US5977101 A1, 1999 ;
反应条件
sulfuric acid; nitric acid
参考文献
Timperley, Christopher M.; Banks, R. Eric; Young, Ian M.; Haszeldine, Robert N.
Journal of Fluorine Chemistry, 2011 , vol. 132, # 8 p. 541 - 547
反应条件
sulfuric acid; nitric acid
参考文献
Kulkarni, Santosh S.; Newman, Amy Hauck
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 2987 - 2991
反应条件
sodium carbonate in 1,4-dioxane; water Cyclization; Tschitschibabin reaction; 22 h; Heating;
参考文献
Tomoda, Haruhiko; Hirano, Takafumi; Saito, Shojiro; Mutai, Toshiki; Araki, Koji
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 6 p. 1327 - 1334