2-氯-4-羟基-5-甲氧基苯甲醛合成路线 （共 15 条）
反应条件
chloroform; chlorine
参考文献
Raiford; Lichty
Journal of the American Chemical Society, 1930 , vol. 52, p. 4576,4582
参考文献
Raiford; Lichty
Journal of the American Chemical Society, 1930 , vol. 52, p. 4576,4582
反应条件
sodium hydroxide; dihydrogen peroxide und anschliessend mit Na2Cr2O7 in wss.H2SO4;
参考文献
Asp; Lindberg
Acta Chemica Scandinavica (1947-1973), 1950 , vol. 4, p. 60,61
参考文献
Raiford; Perry
Journal of Organic Chemistry, 1942 , vol. 7, p. 354,355
反应条件
1: With AlCl3, aluminium chloride in dichloromethane
T=20°C;
2: With water in dichloromethane
参考文献
PLEXXIKON, INC.
Patent: WO2008/80001 A2, 2008 ;
Location in patent: Page/Page column 92-93 ;
反应条件
potassium carbonate in acetone
1.5 h; Heating / reflux;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2006/63820 A1, 2006 ;
Location in patent: Page/Page column 16-17 ;
反应条件
1: 460 mg / diethyl ether / 48 h / 20 °C
2: sodium methoxide / methanol / 1 h / Heating
View Scheme
参考文献
Smith; Wearne; Wallis
Chemosphere, 1995 , vol. 30, # 1 p. 69 - 80
反应条件
sodium methylate in methanol
Hydrolysis; 1 h; Heating;
参考文献
Smith; Wearne; Wallis
Chemosphere, 1995 , vol. 30, # 1 p. 69 - 80
反应条件
bromine; sodium acetate; acetic acid
参考文献
Raiford; Lichty
Journal of the American Chemical Society, 1930 , vol. 52, p. 4576,4582
参考文献
Raiford; Lichty
Journal of the American Chemical Society, 1930 , vol. 52, p. 4576,4582
