反应条件
1.1: 1H-imidazole / N,N-dimethyl-formamide / 1.75 h / 20 °C 2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.33 h / -78 °C 2.2: 16 h / -78 - 35 °C 3.1: phenyl isocyanate; triethylamine / toluene / 4 h / 20 - 80 °C 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.58 h / 0 °C 5.1: tetrachloromethane; triphenylphosphine / dichloromethane / 0.33 h / 20 - 50 °C 6.1: lithium hydroxide hydrate; water / tetrahydrofuran / 19 h / 20 °C View Scheme
参考文献
Sato, Takanao; Sugimoto, Kenji; Inoue, Asuka; Okudaira, Shinichi; Aoki, Junken; Tokuyama, Hidetoshi
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4323 - 4326
